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Safety Information

246573

Sigma-Aldrich

6,7-Dihydroxycoumarin

98%

Synonym(s):

Cichorigenin, Esculetin

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About This Item

Empirical Formula (Hill Notation):
C9H6O4
CAS Number:
305-01-1
Molecular Weight:
178.14
Beilstein:
152788
EC Number:
206-161-5
MDL number:
MFCD00006874
UNSPSC Code:
12162002
PubChem Substance ID:
24854815
NACRES:
NA.23

Quality Level

100

Assay

98%

form

powder

mp

271-273 °C (lit.)

SMILES string

Oc1cc2OC(=O)C=Cc2cc1O

InChI

1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H

InChI key

ILEDWLMCKZNDJK-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

246573-50G:
246573-1G:
246573-BULK:
246573-VAR:
246573-5G:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3890
BCCL3883
BCCJ3165
BCCG6454
BCCF4903

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Risto O Juvonen et al.
Planta medica, 85(6), 453-464 (2019-02-09)
Scoparone, a major constituent of the Chinese herbal medicine Yin Chen Hao, expresses beneficial effects in experimental models of various diseases. The intrinsic doses and effects of scoparone are dependent on its metabolism, both in humans and animals. We evaluated
Yusuf Erdogdu
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 106, 25-33 (2013-01-29)
In this work, we report a combined experimental and theoretical study on molecular structure, vibrational spectra and electronic properties of Esculetin (ESC). The FT-IR, FT-Raman and FT-NMR spectra have been recorded and analyzed. The molecular geometry, harmonic vibrational frequencies, chemical
Dhamodaran Prabakaran et al.
Biochimie, 95(2), 366-373 (2012-10-20)
Diabetes mellitus is the most common serious metabolic disorder and it is considered to be one of the five leading causes of death in the world. Hyperglycemia-mediated oxidative stress plays a crucial role in diabetic complications. Hence, this study was
Aline Witaicenis et al.
Chemico-biological interactions, 186(2), 211-218 (2010-04-13)
Coumarins comprise a broad class of phenolic compounds that influences the formation and scavenging of reactive oxygen species and the processes involving free radical-mediated injury. In light of the antioxidant and anti-inflammatory properties of esculetin and 4-methylesculetin, the aim of
Chen Wang et al.
Journal of neurochemistry, 121(6), 1007-1013 (2012-03-31)
Previous studies have demonstrated that a natural coumarin compound esculetin (Esc) possesses antioxidant, anti-tumor, and anti-inflammation activities and rescues cultured primary neurons from NMDA toxicity. In this study, we investigated the neuroprotective effects of Esc on cerebral ischemia/reperfusion (I/R) injury
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