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Safety Information

284025

Sigma-Aldrich

Diethylenetriaminepentaacetic dianhydride

98%

Synonym(s):

N,N-Bis[2-(2,6-dioxomorpholino)ethyl]glycine, DTPA anhydride, DTPA dianhydride

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O8
CAS Number:
23911-26-4
Molecular Weight:
357.32
Beilstein:
1230954
MDL number:
MFCD00010697
UNSPSC Code:
12162002
PubChem Substance ID:
24857140
NACRES:
NA.23

Quality Level

200

Assay

98%

form

powder

mp

182-184 °C (lit.)

storage temp.

−20°C

SMILES string

OC(=O)CN(CCN1CC(=O)OC(=O)C1)CCN2CC(=O)OC(=O)C2

InChI

1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)

InChI key

RAZLJUXJEOEYAM-UHFFFAOYSA-N

Related Categories

Application

Employed in the synthesis of macrocyclic ligands and lanthanide complexes that are useful as MRI enhancers.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

284025-BULK:
284025-1G:
284025-VAR:
284025-5G:

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Certificates of Analysis (COA)

Lot/Batch Number
0000420105
0000420104
0000420104
0000420105
0000407142

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Ying-Hsia Shih et al.
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The purpose of this research was to investigate the effectiveness of epidermal growth factor receptor (EGFR) targeted micelles loaded with IR-780 (Cetuximab/IR-780/micelles) for generating tumor targeting, multimodal images, and photothermal therapy (PTT). We initially studied the cellular uptake of these
Farid N Faruqu et al.
Theranostics, 9(6), 1666-1682 (2019-05-01)
Extracellular vesicles, in particular exosomes, have recently gained interest as novel drug delivery vectors due to their biological origin and inherent intercellular biomolecule delivery capability. An in-depth knowledge of their in vivo biodistribution is therefore essential. This work aimed to
Inorganic Chemistry, 33, 5794-5794 (1994)
Yongbo Yang et al.
ACS applied materials & interfaces, 9(28), 23450-23457 (2017-06-29)
A bimodal contrast nanoagent was developed by chelating gadolinium ions to 2-[bis[2-[carboxymethyl-[2-oxo-2-(2-sulfanylethyl-amino)ethyl]amino]ethyl]amino]acetic acid (DTDTPA)-modified CuInS
J Powe et al.
Cancer drug delivery, 1(2), 125-135 (1984-01-01)
Monoclonal antibodies (MAb) and their F(ab')2 fragments to human colorectal carcinoma (CRC) and human melanoma-associated antigens were conjugated to diethylenetriaminepentaacetic acid (DTPA) via an acylation reaction using cyclic DTPA dianhydride. Relative immunoreactivity of the F(ab')2 fragments was as high as
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