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Safety Information

363634

Sigma-Aldrich

Semicarbazide

6 wt. % (on silica gel)

Synonym(s):

Aminourea, Hydrazinecarboxamide, Isosemicarbazide

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About This Item

Linear Formula:
H2NCONHNH2
CAS Number:
57-56-7
Molecular Weight:
75.07
MDL number:
MFCD00042824
UNSPSC Code:
12352125
PubChem Substance ID:
24862206
NACRES:
NA.22

form

powder

Quality Level

100

composition

, 6 wt. % (on silica gel)

SMILES string

NNC(N)=O

InChI

1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5)

InChI key

DUIOPKIIICUYRZ-UHFFFAOYSA-N

Related Categories

Application

  • Antibacterial activity: Semicarbazide derivatives, specifically thiosemicarbazide, exhibit significant antibacterial properties influenced by substituent position. This underscores its application in pharmaceutical synthesis and microbial resistance studies (Janowska et al., 2024).
  • Solar cell performance: The application of semicarbazide hydrochloride in suppressing deep-level traps significantly improves the efficiency of tin-based perovskite solar cells, highlighting its potential in energy materials research (Jia et al., 2023).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

363634-100G:
363634-BULK:
363634-VAR:
363634-25G:

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Certificates of Analysis (COA)

Lot/Batch Number
0000343190
0000343190
0000317479
0000247552
0000247551

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M M Palcic et al.
Progress in brain research, 106, 41-47 (1995-01-01)
The relationship between the soluble copper topaquinone amine oxidases, the membrane bound semicarbazide-sensitive amine oxidases and lysyl oxidase remains unclear. The stereochemical course of substrate oxidation has been determined for each enzyme type and these studies suggest that SSAO and
Palak J Trivedi et al.
Gut, 67(6), 1135-1145 (2017-04-22)
Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of IBD. This clinical association is linked pathologically to the recruitment of mucosal T cells to the liver, via vascular adhesion protein (VAP)-1-dependent enzyme activity. Our aim was to examine the
Sathya Narayanan Patmanathan et al.
Scientific reports, 6, 25650-25650 (2016-05-11)
Oral squamous cell carcinoma (OSCC) is a lethal disease with a 5-year mortality rate of around 50%. Molecular targeted therapies are not in routine use and novel therapeutic targets are required. Our previous microarray data indicated sphingosine 1-phosphate (S1P) metabolism
Christian Carpéné et al.
Journal of physiology and biochemistry, 73(3), 475-486 (2016-10-22)
Semicarbazide-sensitive amine oxidase (SSAO), identical to primary amine oxidase or vascular adhesion protein-1, is a membrane enzyme that generates hydrogen peroxide. SSAO is highly expressed at the adipocyte surface, and its plasma levels increase with type 2 diabetes. Since visceral
Jonas M Fuks et al.
PLoS pathogens, 8(12), e1003051-e1003051 (2012-12-14)
During acute infection in human and animal hosts, the obligate intracellular protozoan Toxoplasma gondii infects a variety of cell types, including leukocytes. Poised to respond to invading pathogens, dendritic cells (DC) may also be exploited by T. gondii for spread
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