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Safety Information

531537

Sigma-Aldrich

1,2-Epoxy-2-methylpropane

97%

Synonym(s):

1,2-Epoxy-isobutane, 2,2-Dimethyloxirane, Isobutylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
558-30-5
Molecular Weight:
72.11
EC Number:
209-193-8
MDL number:
MFCD00066354
UNSPSC Code:
12162002
PubChem Substance ID:
24877823
NACRES:
NA.23

Quality Level

200

Assay

97%

refractive index

n20/D 1.374 (lit.)

bp

50-51 °C (lit.)

density

0.812 g/mL at 25 °C (lit.)

SMILES string

CC1(C)CO1

InChI

1S/C4H8O/c1-4(2)3-5-4/h3H2,1-2H3

InChI key

GELKGHVAFRCJNA-UHFFFAOYSA-N

Related Categories

Signal Word

Danger

Hazard Statements

H225,H314,H341,H351

Hazard Classifications

Carc. 2 - Flam. Liq. 2 - Muta. 2 - Skin Corr. 1C

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-26.5 °F

Flash Point(C)

-32.5 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

JAN Code

531537-VAR:
531537-10G:
531537-BULK:
531537-50G:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK7106
BCCG9517
BCCD2350
BCCB6280
BCBV5875

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M Cornet et al.
Archives of toxicology, 65(4), 263-267 (1991-01-01)
Until now, no data are available concerning the biotransformation and toxicity of 2-methylpropene (or isobutene), a gaseous alkene widely used in industry (rubber, fuel additives, plastic polymers, adhesives, antioxidants). In this work, the biotransformation of 2-methylpropene (MP) has been studied
Paul R Carlier et al.
The Journal of organic chemistry, 71(4), 1592-1597 (2006-02-14)
Protonated epoxides feature prominently in organic chemistry as reactive intermediates. Herein, we describe 10 protonated epoxides using B3LYP, MP2, and CCSD/6-311++G calculations. Relative to CCSD, B3LYP consistently overestimates the C2-O bond length. Protonated 2-methyl-1,2-epoxypropane is the most problematic species studied
U Jorritsma et al.
Mutagenesis, 10(2), 101-104 (1995-03-01)
2-Methylpropene (isobutene), a gaseous compound widely used in chemical industries, is metabolized to the epoxide 2-methyl-1,2-epoxypropane. The parent compound has previously been shown to be non-mutagenic in a modified Ames test, whereas the epoxide metabolite gave a positive result. In
M Cornet et al.
Chemical research in toxicology, 8(7), 987-992 (1995-10-01)
The biotransformation of 2-methylpropene, a gaseous alkene widely used in industry, was investigated in vitro in liver tissue of rats, mice, and humans. Interspecies comparison revealed that the lowest levels of the primary epoxide metabolite were detected in incubations of
M Cornet et al.
Mutation research, 271(3), 213-221 (1992-06-01)
The mutagenic properties of 2-methylpropene (MP) and 2-methyl-1,2- epoxypropane (MEP) were investigated in the Salmonella assay. A simple exposure system, consisting of gastight tissue culture flasks, was used. This method has the advantage that the volatile test chemical is present
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