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Key Documents

Safety Information

534641

Sigma-Aldrich

Amano Lipase PS, from Burkholderia cepacia

≥23,000  U/g, pH 7.0, 50 °C (Optimum pH and temperature)

Synonym(s):

APS-BCL, Pseudomonas cepacia (APS-PCL)

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About This Item

MDL number:
MFCD02685894
UNSPSC Code:
12352204
NACRES:
NA.22

Quality Level

100

specific activity

≥23,000  U/g, pH 7.0, 50 °C (Optimum pH and temperature)

Application

Shvo′s Catalyst
Amano Lipase PS is generally used in the enantioselective transesterification and hydrolysis. Applications include:
  • Lipase catalyzed transesterification of prochiral pyrimidine acyclonucleoside.
  • Lipase catalyzed hydrolysis of diacetylated pyrimidine acyclonucleosides.
  • Enantiomer selective acylation of racemic alcohols in continuous-flow bioreactors.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

534641-VAR:
534641-50G:
534641-10G:
534641-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW3366
MKCV2706
MKCT1457
MKCP8671
MKCT3338

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Lipase-catalyzed enantioselective transesterification of prochiral 1-((1, 3-dihydroxypropan-2-yloxy) methyl)-5, 6, 7, 8-tetrahydroquinazoline-2, 4 (1H, 3H)-dione in ionic liquids.
Kolodziejska, et al.
Chirality, 30(2), 206-214 (2018)
Immobilization of lipase from Burkholderia cepacia into calcium carbonate microcapsule and its use for enzymatic reactions in organic and aqueous media.
Fujiwara M, et al.
Journal of Molecular Catalysis. B, Enzymatic, 109, 94-100 (2014)
Reverse Stereoselectivity in the Lipase-Catalyzed Hydrolysis of Diacetylated Pyrimidine Acyclonucleosides.
Kolodziejska et al.
ChemCatChem, 8(23), 3644-3649 (2016)
Enantiomer selective acylation of racemic alcohols by lipases in continuous-flow bioreactors.
Csajagi C, et al.
Tetrahedron Asymmetry, 19(2), 237-246 (2008)
Dominik Koszelewski et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(43), 10156-10164 (2019-05-29)
A new protocol based on lipase-catalyzed tandem reaction toward α,β-enones/enoesters is presented. For the synthesis of the desired products the tandem process based on enzyme-catalyzed hydrolysis and Knoevenagel reaction starting from enol acetates and aldehyde is developed. The relevant impact

Articles

Shvo’s Catalyst

Efficient epimerization catalyst for enzyme mediated dynamic kinetic resolution (DKR).

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