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Safety Information

852279

Sigma-Aldrich

2′-Deoxyinosine

99%

Synonym(s):

9-(2-Deoxy-β-D-ribofuranosyl)hypoxanthine

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About This Item

Empirical Formula (Hill Notation):
C10H12N4O4
CAS Number:
890-38-0
Molecular Weight:
252.23
Beilstein:
33517
EC Number:
212-964-1
MDL number:
MFCD00005762
UNSPSC Code:
12352103
PubChem Substance ID:
329769363

Quality Level

100

Assay

99%

form

powder

functional group

ether
hydroxyl

SMILES string

OC[C@H]1O[C@H](C[C@@H]1O)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1

InChI key

VGONTNSXDCQUGY-RRKCRQDMSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

852279-100MG:
852279-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
10143LR
08023MN
04051TQ
14790DQ
06753MQ

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Chia-Chia Lee et al.
DNA repair, 9(10), 1073-1079 (2010-08-11)
Deoxyinosine (dI) in DNA can arise from hydrolytic or nitrosative deamination of deoxyadenosine. It is excised in a repair pathway that is initiated by endonuclease V, the nfi gene product, in Escherichia coli. Repair was studied in vitro using M13mp18
Raphaelle Fanciullino et al.
Pharmaceutical research, 22(12), 2051-2057 (2005-10-14)
The aims of this study were to develop a stealth, pegylated liposomal formulation of 2'-deoxyinosine (d-Ino), a 5-fluorouracil (5-FU) modulator, to evaluate its efficacy in vitro and in tumor-bearing mice, and to study its pharmacokinetics in rats. After designing a
L S Bazar et al.
Electrophoresis, 20(6), 1141-1148 (1999-06-25)
We introduce a novel experimental strategy for DNA mutation detection named the Mismatch Identification DNA Analysis System (MIDAS) [1, 2], which has an associated isothermal probe amplification step to increase target DNA detection sensitivity to attomole levels. MIDAS exploits DNA
Susen Hartmann et al.
Clinical chemistry, 52(6), 1127-1137 (2006-04-15)
Clinical presentation and disease severity in disorders of purine and pyrimidine metabolism vary considerably. We present a method that allows comprehensive, sensitive, and specific diagnosis of the entire spectrum of abnormalities in purine and pyrimidine metabolism in 1 analytical run.
Kok Seong Lim et al.
Nature protocols, 1(4), 1995-2002 (2007-05-10)
Several studies examining DNA deamination have published levels of 2'-deoxyinosine that illustrated a large variation between studies. Most of them are the result of artifactual DNA deamination that occurs during the process of sample preparation, particularly acid hydrolysis. This protocol
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