Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

Safety Information

900275

Sigma-Aldrich

(t-Bu)PhCPhos

95%

Synonym(s):

2-[(tert-Butyl)phenylphosphino]-2′,6′-bis(N,N-dimethylamino)biphenyl

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C26H33N2P
CAS Number:
1660153-91-2
Molecular Weight:
404.53
MDL number:
MFCD29905429
UNSPSC Code:
12352200
NACRES:
NA.22
form:
powder or crystals
Assay:
95%

Quality Level

100

Assay

95%

form

powder or crystals

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings
reagent type: ligand

mp

112 °C

functional group

phosphine

SMILES string

P(C(C)(C)C)(c2c(cccc2)c3c(cccc3N(C)C)N(C)C)c1ccccc1

InChI

1S/C26H33N2P/c1-26(2,3)29(20-14-9-8-10-15-20)24-19-12-11-16-21(24)25-22(27(4)5)17-13-18-23(25)28(6)7/h8-19H,1-7H3

Application

(t-Bu)PhCPhos is the Pd G3 complex, from the Buchwald group offers best-in-class performance in the arylation of sterically hindered primary amines.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H413

Hazard Classifications

Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

900275-250MG:
900275-VAR:
900275-1G:
900275-BULK:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCX0161

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Paula Ruiz-Castillo et al.
Journal of the American Chemical Society, 137(8), 3085-3092 (2015-02-05)
We report the Pd-catalyzed arylation of very hindered α,α,α-trisubstituted primary amines. Kinetics-based mechanistic analysis and rational design have led to the development of two biarylphosphine ligands that allow the transformation to proceed with excellent efficiency. The process was effective in

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service