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Safety Information

B65705

Sigma-Aldrich

2-Bromoethylamine hydrobromide

99%

Synonym(s):

2-Aminoethyl bromide hydrobromide

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About This Item

Linear Formula:
BrCH2CH2NH2 · HBr
CAS Number:
2576-47-8
Molecular Weight:
204.89
Beilstein:
3607605
EC Number:
219-924-2
MDL number:
MFCD00012886
UNSPSC Code:
12352100
PubChem Substance ID:
24891920
NACRES:
NA.22

Quality Level

200

Assay

99%

form

crystals

mp

170-175 °C (lit.)

SMILES string

Br.NCCBr

InChI

1S/C2H6BrN.BrH/c3-1-2-4;/h1-2,4H2;1H

InChI key

WJAXXWSZNSFVNG-UHFFFAOYSA-N

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Application

2-Bromoethylamine hydrobromide can be used as a reactant to synthesize:
  • Thiazolines and thiazines via tandem S-alkylation-cyclodeamination of thioamides/haloamines.
  • Optically active tertiary phosphines via cesium hydroxide-catalyzed P-alkylation of secondary phosphines.
  • Secondary amines via CsOH-promoted chemoselective mono-N-alkylation of primary amines, diamines, and polyamines.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

142.9 °F - Pensky-Martens closed cup

Flash Point(C)

61.6 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

B65705-100G:
B65705-BULK:
B65705-25KG:
B65705-50KG:
B65705-100KG:
B65705-VAR:
B65705-25G:
B65705-10KG:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM6662
WXBF2589V
WXBF4883V
WXBF3745V
BCCM5136

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Veterinary journal (London, England : 1997), 204(2), 157-161 (2015-04-30)
In Korea, porcine reproductive and respiratory syndrome (PRRS) is caused by European (type 1) and North American (type 2) strains of PRRS virus (PRRSV). In the present study, the efficacy of a multi-strain PRRSV vaccine inactivated with binary ethylenimine (BEI)
S Garrod et al.
Magnetic resonance in medicine, 45(5), 781-790 (2001-04-27)
The metabolic consequences of xenobiotic-induced toxicity were investigated using high-resolution magic angle spinning (MAS) NMR spectroscopy of intact tissue. Renal papillary necrosis (RPN) was induced in Sprague-Dawley rats (n = 12) via a single i.p. dose of 250 mg/kg 2-bromoethanamine
Daisuke Sasaki et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 16(7), 553-566 (2011-10-01)
To aid in evaluating the performance of biomarkers, we measured kidney injury biomarkers in rat models of drug-induced acute kidney injury. Rats were treated with site-specific nephrotoxins, puromycin, gentamicin, cisplatin, or 2-bromoethylamine. Fifteen biomarkers (β-2-microglobulin, calbindin, clusterin, cystatin-C, KIM-1, GST-α
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