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Safety Information

L032100

Sigma-Aldrich

DCI Activator

0.5 M

Synonym(s):

DCI activator solution

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About This Item

UNSPSC Code:
41116105
NACRES:
NA.21

Quality Level

200

type

for DNA synthesis
for DNA synthesis

product line

Proligo Reagents

storage condition

dry at room temperature

concentration

58-64 g/L (DCI content, titration)

impurities

≤30 ppm water content (Karl Fischer)
≤30 ppm water content (Karl Fischer)

color

clear
clear

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General description

Activator solution, containing powerful activators like 4,5-dicyanoimidazole(DCI), 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) or5-(Ethylthio)-1H-tetrazole (ETT) in acetonitrile, are mixed with solutions ofphosphoramidites during the extension step. The activator reacts with theamidite group to form a highly reactive intermediate. The intermediate thenforms an internucleotide bond with the detritylated 5′hydroxyl group of thegrowing oligonucleotide chain.

Preparation Note

Dicycanoimidazole /Acetonitrile 6/100 (w/v)

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

41.0 °F

Flash Point(C)

5 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

L080251-04:4548173225692
L080251-01:4548173279060
L032100-4X2.5L:4548173369792
L032100-2.5L:

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Certificates of Analysis (COA)

Lot/Batch Number
HMBK4326
HMBK4111
HMBK3694
HMBK3693
HMBK2447

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