M56557

4-Methylmorpholine

ReagentPlus^®, 99%

• Synonym(s): N-Methylmorpholine, NMM
• Empirical Formula (Hill Notation): C₅H₁₁NO
• CAS Number: 109-02-4
• Molecular Weight: 101.15
• Beilstein: 102719
• EC Number: 203-640-0
• MDL number: MFCD00006175
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654399
• NACRES: NA.22
• Assay: 99%
• bp: 115-116 °C/750 mmHg (lit.)
• vapor pressure: 18 mmHg ( 20 °C)

Properties

• vapor density: >1 (vs air)
• Quality Level: 200
• vapor pressure: 18 mmHg ( 20 °C)
• product line: ReagentPlus^®
• Assay: 99%
• form: liquid
• refractive index: n20/D 1.435 (lit.)
• bp: 115-116 °C/750 mmHg (lit.)
• mp: −66 °C (lit.)
• density: 0.92 g/mL at 25 °C (lit.)
• SMILES string: CN1CCOCC1
• InChI: 1S/C5H11NO/c1-6-2-4-7-5-3-6/h2-5H2,1H3
• InChI key: SJRJJKPEHAURKC-UHFFFAOYSA-N

Description

General description

4-methylmorpholine, also known as N-Methylmorpholine, is a cyclic tertiary amine and is commonly used as a highly valuable solvent and a fine chemical for cellulose.

Application

4-Methylmorpholine can be used to synthesize N-butyl-N-methylmorpholinium bromide by reacting with bromobutane.

4-methylmorpholine is used:

• in the synthesis of N-methylmorpholine-N-oxide (NMMO)
• as an effective and inexpensive additive for highly enantioselective arylation of aryl aldehydes catalyzed by the (S)-H8-BINOL-Ti(Oi-Pr)2 complex

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302,H314
• Precautionary Statements: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 53.6 °F - closed cup - DIN 51755 Part 1
• Flash Point(C): 12 °C - closed cup - DIN 51755 Part 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves