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Safety Information

V1309

Sigma-Aldrich

3,4-Dimethoxybenzylamine

97%

Synonym(s):

Veratrylamine

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About This Item

Linear Formula:
3,4-(CH3O)2C6H3CH2NH2
CAS Number:
5763-61-1
Molecular Weight:
167.21
Beilstein:
511575
EC Number:
227-287-7
MDL number:
MFCD00008116
UNSPSC Code:
12352100
PubChem Substance ID:
24900715
NACRES:
NA.22

Quality Level

100

Assay

97%

refractive index

n20/D 1.556 (lit.)

bp

281-284 °C (lit.)

density

1.109 g/mL at 25 °C (lit.)

SMILES string

COc1ccc(CN)cc1OC

InChI

1S/C9H13NO2/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-5H,6,10H2,1-2H3

InChI key

DIVNUTGTTIRPQA-UHFFFAOYSA-N

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Application

<ul>
<li><strong>Fluorescence Derivatization for Serotonin Determination:</strong> 3,4-Dimethoxybenzylamine is employed as a sensitive pre-column fluorescence derivatization reagent for measuring serotonin levels in human platelet-poor plasma, enhancing detection sensitivity and specificity (Ishida et al., 1997).</li>
<li><strong>Spectrofluorimetric Analysis of 5-Hydroxyindoles:</strong> This compound serves as a selective fluorogenic reagent for the spectrofluorimetric determination of 5-hydroxyindoles, contributing to accurate and selective analysis techniques in clinical and biochemical studies (Ishida et al., 1991).</li>
</ul>

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

V1309-5G:
V1309-BULK:
V1309-VAR:
V1309-25G:

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Certificates of Analysis (COA)

Lot/Batch Number
SHBL4574
SHBB6407V
39296DKV
39296DK
11415TE

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J Ishida et al.
Journal of chromatography. B, Biomedical sciences and applications, 692(1), 31-36 (1997-04-25)
3,4-Dimethoxybenzylamine is shown to be a highly sensitive pre-column fluorescence derivatization reagent for the determination of serotonin in plasma by high-performance liquid chromatography. The reagent reacts selectively with 5-hydroxyindoles including serotonin in slightly alkaline media in the presence of potassium
A M Feigin et al.
Neuroreport, 6(16), 2134-2136 (1995-11-13)
The irritating, pungent compound, capsaicin (10-20 microM), induces the formation of non-selective ion channels with a wide variety of conductances in protein-free lipid bilayers form from a mixture of zwitterionic phospholipids. The channel-forming activity of capsaicin and four of its
J Ishida et al.
The Analyst, 116(3), 301-304 (1991-03-01)
A spectrofluorimetric method has been developed for the sensitive and selective determination of 5-hydroxyindoles; the method is based on the reaction of 5-hydroxyindoles in a weakly alkaline solution (pH 9.0) with aromatic methylamines in the presence of potassium hexacyanoferrate(III) and

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