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Safety Information

W224511

Sigma-Aldrich

Carvacrol

natural, 99%, FG

Synonym(s):

5-Isopropyl-2-methylphenol

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About This Item

Linear Formula:
(CH3)2CHC6H3(CH3)OH
CAS Number:
499-75-2
Molecular Weight:
150.22
FEMA Number:
2245
Beilstein:
1860514
EC Number:
207-889-6
Council of Europe no.:
2055
MDL number:
MFCD00002236
UNSPSC Code:
12164502
PubChem Substance ID:
329830467
Flavis number:
4.031
NACRES:
NA.21
Organoleptic:
camphoraceous; woody; spicy
grade:
FG
Fragrance grade
Halal
Kosher
natural
Agency:
follows IFRA guidelines
meets purity specifications of JECFA
food allergen:
no known allergens

grade

FG
Fragrance grade
Halal
Kosher
natural

Quality Level

300

Agency

follows IFRA guidelines
meets purity specifications of JECFA

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117

Assay

99%

refractive index

n20/D 1.522 (lit.)

bp

236-237 °C (lit.)

mp

3-4 °C (lit.)

density

0.976 g/mL at 20 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

carvacrol

Organoleptic

camphoraceous; woody; spicy

SMILES string

CC(C)c1ccc(C)c(O)c1

InChI

1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

InChI key

RECUKUPTGUEGMW-UHFFFAOYSA-N

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General description

Carvacrol is one of the key constituents of basil and thyme essential oils. It is one of the compounds that may be responsible for antioxidant activities of these oils.

Application


  • Prophylactic efficacy of baicalin and carvacrol against Salmonella Typhimurium biofilm on food and food contact surfaces.: The study explores the effectiveness of carvacrol in preventing biofilm formation by Salmonella Typhimurium, with implications for food safety (Ashrafudoulla et al., 2024).


Signal Word

Danger

Hazard Statements

H302,H314,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

W224511-SAMPLE-K:
W224511-VAR-K:
W224511-1KG-K:4548173335452
W224511-100G-K:4548173335438
W224511-10KG-K:4548173335445
W224511-BULK-K:

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Certificates of Analysis (COA)

Lot/Batch Number
SHBL6147
SHBL4915
MKCG2266
MKCD4767
MKBT0467V

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USP

1667213

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Eugenol ReagentPlus®, 99%

Sigma-Aldrich

E51791

Eugenol

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Sigma-Aldrich

W306509

Thyme oil

Thymoquinone ≥98%

Sigma-Aldrich

274666

Thymoquinone

Identification of volatile components in basil (Ocimum basilicum L.) and thyme leaves (Thymus vulgaris L.) and their antioxidant properties.
Lee SJ, et al.
Food Chemistry, 91(1), 131-137 (2005)
Ademola Oladunjoye et al.
Poultry science, 92(5), 1357-1365 (2013-04-11)
In the present study, low concentrations of carvacrol (0.025 to 0.2%) and lauric arginate (LAE; 25 to 200 ppm) were tested at 4, 22, and 45°C in a broth model, and higher concentrations of carvacrol (0.1 to 5%) and LAE
Josué de Moraes et al.
Parasitology research, 112(2), 603-610 (2012-10-23)
Blood flukes of the genus Schistosoma are the causative agents of human schistosomiasis, a debilitating disease that afflicts over 200 million people worldwide. Praziquantel is the drug of choice but concerns over praziquantel resistance have renewed interest in the search
Samed Koc et al.
Veterinary parasitology, 193(1-3), 316-319 (2012-12-12)
The acaricidal activity of an essential oil obtained from aerial parts of Origanum bilgeri P.H. Davis (Lamiaceae), an endemic species in Turkey, and its major constituents, carvacrol was evaluated against unfed adults Rhipicephalus turanicus Pomerantzev (Acari: Ixodidae) collected from Kepez
Wei-Zhe Liang et al.
Toxicology, 303, 152-161 (2012-11-14)
Carvacrol is one of the main substances of essential oil which triggers intracellular Ca(2+) mobilization and causes cytotoxicity in diverse cell models. However, the mechanism of carvacrol-induced Ca(2+) movement and cytotoxicity is not fully understood. This study examined the effect
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