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330707

Avanti

SPLASH™ LIPIDOMIX™ Mass Spec Standard

Avanti Research™ - A Croda Brand

Synonym(s):

SPLASH™ LIPIDOMIX™ Mass Spec Standard, Single-vial Prepared Lipidomic Analytical Standard for Human plasma lipids

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About This Item

UNSPSC Code:
41116107
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (330707-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

1 mg/mL (330707-1EA)

technique(s)

mass spectrometry (MS): suitable

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

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General description

Make a splash in your lab and dive right into Lipidomics with our easy to use mixture of deuterium labeled lipids. The SPLASH™ LIPIDOMIX™ Mass Spec Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample. This internal standard mixture was developed in collaboration with Kim Ekroos (Zora Biosciences).

Application

SPLASH™ LIPIDOMIX™ Mass Spec Standard has been used:
  • as an internal standard for non-alcoholic fatty liver disease (NAFLD) signature analysis from mice and human samples
  • as an internal standard in the quantification of phospholipids from duodenum, liver, and adipose tissue using ultra performance liquid chromatography quadrupole-time of-flight mass spectrometry (UPLC-q-Tof MS)
  • in human cell lines prior to lipid analysis by liquid chromatography-mass spectrometry (LC-MS) analysis

Features and Benefits

  • Save time: pre-mixed internal standards.
  • Save money: 1 vial is sufficient for 100 plasma samples.
  • Exact concentrations provided for quantitative lipidomic analysis.
  • Applicable to multiple MS approaches.
  • Concentration of each lipid class optimized for plasma analysis.

Packaging

2 mL Amber Glass Sealed Ampule (330707-1EA)

Components

The SPLASH LIPIDOMIX Mass Spec Standard is supplied in 1 mL of methanol and contains the following components:

Mixture ComponentTarget Conc. (μg/mL)
  • 15:0-18:1(d7) PC160
  • 15:0-18:1(d7) PE5
  • 15:0-18:1(d7) PS5
  • 15:0-18:1(d7) PG30
  • 15:0-18:1(d7) PI10
  • 15:0-18:1(d7) PA7
  • 18:1(d7) LPC25
  • 18:1(d7) LPE5
  • 18:1(d7) Chol Ester350
  • 18:1(d7) MG2
  • 15:0-18:1(d7) DG10
  • 15:0-18:1(d7)-15:0 TG55
  • 18:1(d9) SM30
  • Cholesterol (d7)100

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

Kit Components Also Available Separately

Product No.
Description
SDS
  • 791637C15:0-18:1-d7-PC, Avanti Research™ - A Croda Brand 160μg/mLSDS
  • 791638C15:0-18:1-d7-PE, Avanti Research™ - A Croda Brand 5μg/mLSDS
  • 791639C15:0-18:1-d7-PS, Avanti Research™ - A Croda Brand 5μg/mLSDS
  • 791640C15:0-18:1-d7-PG, Avanti Research™ - A Croda Brand 791640C 30μg/mLSDS
  • 791641C15:0-18:1-d7-PI, Avanti Research™ - A Croda Brand 10μg/mLSDS
  • 791642C15:0-18:1-d7-PA, Avanti Research™ - A Croda Brand 7μg/mLSDS
  • 791643C18:1-d7 Lyso PC, Avanti Research™ - A Croda Brand 25μg/mLSDS
  • 791644C18:1-d7 Lyso PE, Avanti Research™ - A Croda Brand 791644C 5μg/mLSDS
  • 791645C18:1-d7-cholesterol, Avanti Research™ - A Croda Brand 791645C 350μg/mLSDS
  • 791646C18:1-d7 MG, Avanti Research™ - A Croda Brand 791646C 2μg/mLSDS
  • 791647C15:0-18:1-d7 DG, Avanti Research™ - A Croda Brand 791647C 10μg/mLSDS
  • 791648C15:0-18:1-d7-15:0 TG, Avanti Research™ - A Croda Brand 791648C 55μg/mLSDS
  • 791649C18:1-d9 SM, Avanti Research™ - A Croda Brand 30μg/mLSDS
  • 700041Pcholesterol-d7, Avanti Research™ - A Croda Brand 100μg/mLSDS
See All (14)

also commonly purchased with this product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Alcohols
Hazardous rank II

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

330707-1EA:4548174017012
330707-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number

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M A López-Bascón et al.
Analytical and bioanalytical chemistry, 412(2), 489-498 (2019-11-25)
Polar lipids, especially glycerophospholipids, constitute the main components of cell membranes and are precursors of signaling molecules in many cellular and physiological processes. For this reason, the development of methods with high capability for detection of polar lipids in biological
Mike Lange et al.
Analytical and bioanalytical chemistry, 412(15), 3573-3584 (2020-04-03)
Lipidomics analysis for large-scale studies aiming at the identification and quantification of natural lipidomes is often performed using LC-MS-based data acquisition. However, the choice of suitable LC-MS method for accurate lipid quantification remains a matter of debate. Here, we performed
Isha H Jain et al.
Cell, 181(3), 716-727 (2020-04-08)
Human cells are able to sense and adapt to variations in oxygen levels. Historically, much research in this field has focused on hypoxia-inducible factor (HIF) signaling and reactive oxygen species (ROS). Here, we perform genome-wide CRISPR growth screens at 21%
Metabolomics Profile and Targeted Lipidomics in Multiple Tissues Associated with Feed Efficiency in Beef Steers
Artegoitia VM, et al.
ACS Omega, 4(2), 3973-3982 (2019)
Tomoki Naito et al.
eLife, 8 (2019-11-15)
Cholesterol is a major structural component of the plasma membrane (PM). The majority of PM cholesterol forms complexes with other PM lipids, making it inaccessible for intracellular transport. Transition of PM cholesterol between accessible and inaccessible pools maintains cellular homeostasis
View All Related Papers

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