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Safety Information

C-033

Supelco

Clonidine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C9H9Cl2N3
CAS Number:
4205-90-7
Molecular Weight:
230.09
MDL number:
MFCD00055059
UNSPSC Code:
41116107
PubChem Substance ID:
329774775
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

ClC1=CC=CC(Cl)=C1NC2=NCCN2

InChI

1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)

InChI key

GJSURZIOUXUGAL-UHFFFAOYSA-N

Gene Information

human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Related Categories

General description

Clonidine is a pharmaceutical drug used to treat a wide variety of conditions including hypertension, ADHD, insomnia, chemical withdrawal, and anxiety. Clonidine is often prescribed in combination with other drugs, depending on the clinical condition. This analytical reference standard is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to pharmaceutical research.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Alcohols
Hazardous rank II

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

C-033-CC:
C-033-1ML:4548173319827

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In response.
Gershom Koman
Pain physician, 16(2), E120-E120 (2013-03-21)
Shahram Borjian Boroojeny et al.
JPMA. The Journal of the Pakistan Medical Association, 62(12), 1285-1288 (2013-07-23)
To evaluate the efficacy of preoperative oral clonidine (5 g/kg) in preventing ocular hypertension in the early period after cataract surgery with posterior chamber intraocular lens implantation under general anaesthesia. This was a randomized double-blind clinical trial comprising of 62
Zoher M Naja et al.
Anesthesia and analgesia, 117(1), 252-258 (2013-05-02)
Paravertebral blocks (PVBs) have been introduced as an alternative to general anesthesia for breast cancer surgeries. The addition of clonidine as an adjuvant in PVBs may enhance quality and duration of analgesia and significantly reduce the consumption of analgesics after
Adekola Alao et al.
International journal of psychiatry in medicine, 44(2), 165-169 (2013-02-19)
To describe the successful treatment of PTSD associated nightmares in two patients with PTSD. The report of the successful use of clonidine to treat PTSD associated nightmares among two Veterans following combat exposure. Clonidine, a centrally acting alpha-agonist agent used
Mutasim Al-Ghazawi et al.
International journal of clinical pharmacology and therapeutics, 51(3), 255-262 (2013-02-06)
To assess the bioequivalence of two Tizanidine 4 mg tablet formulations (Tizanidine® of the Pharma International company, as test product, and Sirdalud® of Novartis as a reference product), and to investigate possible effects of smoking on pharmacokinetics of tizanidine. A
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