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233490

Sigma-Aldrich

Coagulation Factor XII, Human Plasma

Coagulation Factor XII, Human Plasma, CAS 9001-30-3, is a native coagulation factor XI that once activated (principally by kallikrein), is converted to Factor α-XIIa.

Synonym(s):

Coagulation Factor XII, Human Plasma

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About This Item

CAS Number:
9001-30-3
UNSPSC Code:
12352202
NACRES:
NA.42

Quality Level

100

form

liquid

specific activity

≥20 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−70°C

General description

Coagulation Factor XII, Human Plasma, CAS 9001-30-3, is a native coagulation factor XI that once activated (principally by kallikrein), is converted to Factor α-XIIa.
Native coagulation factor XII from human plasma. A single-chain polypeptide which, once activated (principally from the action of kallikrein), is converted to Factor α-XIIa. Factor α-XIIa then converts Factor XI to Factor XIa.
Native coagulation factor XII from human plasma. A single-chain polypeptide, which once activated (principally from the action of kallikrein) is converted to Factor α-XIIa. Factor α-XIIa then converts Factor XI to Factor XIa.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Unit Definition

Specific activity is measured by clotting assay and compared to a standard curve produced using normal pooled human plasma.

Physical form

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Analysis Note

single band by SDS-PAGE

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

233490-0MG:
233490-UG:
233490-500UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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