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341578

Sigma-Aldrich

Fibrinogen, Plasminogen-Depleted, Human Plasma

Plasminogen-Depleted fibrinogen is a native fibrinogen from which plasminogen is depleted using a Lys-agarose column. Contains ≥ 95% clottable proteins.

Synonym(s):

Fibrinogen, Plasminogen-Depleted, Human Plasma

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About This Item

CAS Number:
9001-32-5
MDL number:
MFCD00012459
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

human plasma

Quality Level

200

Assay

≥95% (Clottable proteins)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

water: 25 mg/mL

shipped in

wet ice

storage temp.

2-8°C

General description

Native fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Contains ≥ 95% clottable proteins.
Native fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is found at elevated levels during pregnancy, after surgery trauma, or in cases of myocardial infarction. It is found at decreased levels in cases of liver cirrhosis and serum hepatitis. The plasminogen was depleted using a Lys-agarose column.

Warning

Toxicity: Harmful (C)

Preparation Note

To prevent clot formation, warm the H₂O and the fibrinogen to 37°C prior to dissolution.

Reconstitution

Following reconstitution, aliquot and freeze (-70°C) for long term storage or store at room temperature (20°C) for short-term storage. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -70°C. Do not store solutions on ice; precipitation will occur. Stock solutions stored at -70°C should be thawed in a water bath maintained at 37°C.

Analysis Note

homogeneous by SDS-PAGE

Other Notes

Wang, H., et al. 1995. J. Infect. Dis.171, 85.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

341578-MG:
341578-1GM:
341578-0GM:
970814-1GM:
341578-500MG:

Certificates of Analysis (COA)

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