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Safety Information

642511

Sigma-Aldrich

L-3,3′,5-Triiodothyronine free acid

≥97% (HPLC), solid, respiratory activity stimulator, Calbiochem®

Synonym(s):

L-3,3′,5-Triiodothyronine, Free Acid, High Purity, T₃

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About This Item

Empirical Formula (Hill Notation):
C15H12I3NO4
CAS Number:
6893-02-3
Molecular Weight:
650.97
MDL number:
MFCD00002593
UNSPSC Code:
12352106
NACRES:
NA.77

Product Name

L-3,3′,5-Triiodothyronine, Free Acid, High Purity, Chromatographically purified.

Quality Level

100

Assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white to off-white

solubility

0.1 M NaOH: 10 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

Ic1c(c(cc(c1)CC([N+H3])C(=O)[O-])I)Oc2cc(c(cc2)O)I

InChI

1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)

InChI key

AUYYCJSJGJYCDS-UHFFFAOYSA-N

General description

Chromatographically purified.
Chromatographically purified. Stimulates respiratory activity at the mitochondrial level.

Biochem/physiol Actions

Cell permeable: no
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-70°C) under an inert gas for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 6 months at -70°C or for up to 2 weeks at 4°C.

Other Notes

Rodriguez, E.R., et al. 1994. Biochem. Biophys. Res. Commun.205, 1899.
Williams, G.R., et al. 1994. Endocrinology135, 2375.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H372

Precautionary Statements

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1

Target Organs

Thyroid,Cardio-vascular system,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

642511-VMG:
642511-10MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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