8.03541

Dichloroacetic acid

for synthesis

• Synonym(s): Dichloroacetic acid
• Empirical Formula (Hill Notation): C₂H₂Cl₂O₂
• CAS Number: 79-43-6
• Molecular Weight: 128.94
• MDL number: MFCD00004223
• UNSPSC Code: 12352106
• EC Index Number: 201-207-0
• NACRES: NA.22
• pH: 1.2 (20 °C, 129 g/L in H₂O)

Properties

• vapor pressure: 0.19 hPa ( 20 °C)
• Quality Level: 200
• Assay: ≥98.0% (GC)
• form: liquid
• potency: 2820 mg/kg LD₅₀, oral (Rat)
• pH: 1.2 (20 °C, 129 g/L in H₂O)
• bp: 192 °C/1013 hPa (decomposes)
• mp: -4 °C
• density: 1.57 g/cm³ at 20 °C
• storage temp.: 2-30°C
• SMILES string: ClC(Cl)C(=O)O
• InChI: 1S/C2H2Cl2O2/c3-1(4)2(5)6/h1H,(H,5,6)
• InChI key: JXTHNDFMNIQAHM-UHFFFAOYSA-N

Description

Application

• Controlled drug release systems: Research includes the application of Dichloroacetic acid in the synthesis of sulfonated polyether ketone membranes that are embedded with nalidixic acid, highlighting its utility in developing emerging controlled drug releasers in medical applications (Padinjarathil et al., 2023).

Linkage

Replaces: DX0653

Analysis Note

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.560 - 1.570
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Safety Information

• Pictograms: GHS05,GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H290 - H311 - H314 - H335 - H351 - H360FD - H362 - H373 - H410
• Precautionary Statements: P263 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 3 - Carc. 2 - Eye Dam. 1 - Lact. - Met. Corr. 1 - Repr. 1B - Skin Corr. 1 - STOT RE 2 Oral - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup