AG774

Orexin-A, control peptide for AB3098

• UNSPSC Code: 12352200
• eCl@ss: 32160405
• NACRES: NA.28

Properties

• biological source: mouse
• Quality Level: 100
• form: liquid
• manufacturer/tradename: Chemicon^®
• technique(s): inhibition assay: suitable (peptide)
• NCBI accession no.: NM_001524.1
• UniProt accession no.: O43612

Description

General description

18 amino acid peptide from the amino terminus of mouse Orexin-A.

Orexin-A control peptide.

Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (1). Orexin-A and Orexin-B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. Prepro-orexin is an 130 aa peptide with a putative 33 aa secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis (1). These neuropeptides bind and activate two closely related Orexin receptors--G protein coupled receptors (GPCRs) OX1R and OX2R.

Application

Blocking peptide for AB3098.

Optimal working concentration must be determined by the end user.

Physical form

Liquid in PBS, pH 7.5

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable