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Safety Information

34135

Supelco

Deepoxy-deoxynivalenol solution

~50 μg/mL in acetonitrile, analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-trichothec-9,12-dien-8-one solution, DOM-1

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About This Item

Empirical Formula (Hill Notation):
C15H20O5
CAS Number:
88054-24-4
Molecular Weight:
280.32
EC Number:
200-835-2
MDL number:
MFCD07364056
UNSPSC Code:
85151701
PubChem Substance ID:
329754841
NACRES:
NA.24

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

concentration

~50 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)(C3=C)[C@@]2(CO)[C@H](O)C1=O

InChI

1S/C15H20O5/c1-7-4-10-15(6-16,13(19)11(7)18)14(3)5-9(17)12(20-10)8(14)2/h4,9-10,12-13,16-17,19H,2,5-6H2,1,3H3/t9-,10-,12+,13-,14+,15-/m1/s1

InChI key

ZACLXWTWERGCLX-MDUHGFIHSA-N

General description

Certan Vial
Deepoxy-deoxynivalenol is found to be a metabolite of the trichothecene mycotoxin deoxynivalenol, which can be generally found in swine.

Application

Deepoxy-deoxynivalenol solution may be used as internal standard in the determination of trichothecene mycotoxins present in baby foods, using high performance liquid chromatography coupled with mass spectrometry (HPLC/MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Analysis Note

purity : ≥92.5% (HPLC)

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F

Flash Point(C)

2 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

34135-2ML-BULK:
34135-1ML:
34135-1ML-BULK:
34135-2ML:4548173258584

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM1274
BCCL1127
BCCK2480
BCCK2478
BCCK0497

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Wolfram Föllmann et al.
Journal of toxicology and environmental health. Part A, 79(22-23), 1015-1025 (2016-12-08)
Contamination of grains with mycotoxins results in a dietary background exposure of the general population. In occupational settings such as during processing of raw materials as in milling, an additional mycotoxin exposure by inhalation is possible. Biomonitoring is an integrative
Marianne Lauwers et al.
Toxins, 11(3) (2019-03-22)
A reliable and practical multi-method was developed for the quantification of mycotoxins in plasma, urine, and feces of pigs, and plasma and excreta of broiler chickens using liquid chromatography⁻tandem mass spectrometry. The targeted mycotoxins belong to the regulated groups, i.e.
Sandra Debevere et al.
Toxins, 12(6) (2020-06-25)
Ruminal microbiota of cattle are not able to detoxify all mycotoxins. In addition, detoxification can be hampered by adverse ruminal conditions (e.g., low ruminal pH). Hence, in the cattle husbandry, mycotoxin binders and modifiers could be used to prevent animal
Barbara Novak et al.
Toxins, 10(4) (2018-04-12)
Deoxynivalenol (DON) is one of the most prevalent mycotoxins, contaminating cereals and cereal-derived products. Its derivative deepoxy-deoxynivalenol (DOM-1) is produced by certain bacteria, which either occur naturally or are supplemented in feed additive. DON-induced impairments in protein synthesis are particularly
N De Zutter et al.
Scientific reports, 6, 38640-38640 (2016-12-09)
Biotransformation of mycotoxins in animals comprises phase I and phase II metabolisation reactions. For the trichothecene deoxynivalenol (DON), several phase II biotransformation reactions have been described resulting in DON-glutathiones, DON-glucuronides and DON-sulfates made by glutathione-S-transferases, uridine-diphosphoglucuronyl transferases and sulfotransferases, respectively.
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