Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

402915

Sigma-Aldrich

Phthalic acid

ACS reagent, ≥99.5%

Synonym(s):

1,2-Benzenedicarboxylic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C6H4-1,2-(CO2H)2
CAS Number:
88-99-3
Molecular Weight:
166.13
Beilstein:
608199
EC Number:
201-873-2
MDL number:
MFCD00002467
UNSPSC Code:
12352100
PubChem Substance ID:
24865138
NACRES:
NA.21

grade

ACS reagent

Quality Level

200

Assay

≥99.5%

form

powder or crystals

impurities

≤0.05% insolubles
≤0.5% water

ign. residue

≤0.02%

mp

210-211 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤0.001%
nitrate (NO3-): ≤0.005%
sulfate (SO42-): ≤0.005%

cation traces

Fe: ≤0.001%
heavy metals: ≤0.001%

functional group

carboxylic acid

SMILES string

OC(C1=C(C(O)=O)C=CC=C1)=O

InChI

1S/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12)

InChI key

XNGIFLGASWRNHJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Phthalic acid (PA, PTA), also called as 1,2-benzenedicarboxylic acid is an aromatic carboxylic acid. It is the ortho form of the three phthalic acid isomers, the other two being isophthalic acid (meta form) and terephthalic acid (para form). PA is the starting material in the synthesis of plasticizers. A study on toxicity reveals that PA shows in vitro and in vivo toxicity. Its mineralization by photocatalysis using TiO2/UV system has been studied. It also is used as a potential tyrosinase inhibitor.

Application

Phthalic acid may be used as a catalyst for the thiocyanation of aromatics and heteroaromatics and as an interfacial protector for the preparation of ordered mesoporous γ-alumina. It may be used as a model compound in understanding the adsorption of aromatic carboxylic acids on gold surfaces.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

334.4 °F

Flash Point(C)

168 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

402915-250G:
402915-1KG:
402915-BULK:
402915-25G:
402915-VAR:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
WXBF2395V
BCCL2348
WXBF3775V
BCCL0057
BCCJ6485

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A new synthetic procedure for ordered mesoporous γ-alumina using phthalic acid as an interfacial protector.
Huang F, et al.
Materials Letters, 65(2), 244-246 (2011)
Shang-Jun Yin et al.
Enzyme research, 2011, 294724-294724 (2011-06-04)
Tyrosinase inhibition studies are needed due to the medicinal applications such as hyperpigmentation. For probing effective inhibitors of tyrosinase, a combination of computational prediction and enzymatic assay via kinetics was important. We predicted the 3D structure of tyrosinase, used a
Modeling of photocatalytic mineralization of phthalic acid in TiO2 suspension using response surface methodology (RSM).
Abaamrane A, et al.
Desalination and Water Treatment, 53(1), 249-256 (2015)
Phthalic acid as a di-functional organocatalyst for the regioselective thiocyanation of aromatic compounds.
Sajjadifar S, et al.
Scientia Iranica. Transaction C, Chemistry, Chemical Engineering, 21(6), 2005-2005 (2014)
Du Yeon Bang et al.
Toxicological research, 27(4), 191-203 (2011-12-01)
There has been growing concern about the toxicity of phthalate esters. Phthalate esters are being used widely for the production of perfume, nail varnish, hairsprays and other personal/cosmetic uses. Recently, exposure to phthalates has been assessed by analyzing urine for
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service