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66011

Sigma-Aldrich

Alcianblue 8GX solution

for microscopy, 1% in solution (in 3% acetic acid)

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About This Item

CAS Number:
75881-23-1
MDL number:
MFCD00010720
UNSPSC Code:
12171500
PubChem Substance ID:
329760145
NACRES:
MA.02

grade

for microscopy

Quality Level

100

form

liquid

concentration

1% in solution (in 3% acetic acid)

technique(s)

microbe id | staining: suitable

density

0.996-1.016 g/cm3

ε (extinction coefficient)

2.4 at 619 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C
room temp

InChI

1S/C56H68N16S4.4ClH.Cu/c1-65(2)53(66(3)4)73-29-33-17-21-37-41(25-33)49-57-45(37)62-50-43-27-35(31-75-55(69(9)10)70(11)12)19-23-39(43)47(59-50)64-52-44-28-36(32-76-56(71(13)14)72(15)16)20-24-40(44)48(60-52)63-51-42-26-34(18-22-38(42)46(58-51)61-49)30-74-54(67(5)6)68(7)8;;;;;/h17-28H,29-32H2,1-16H3;4*1H;/q+2;;;;;+2/p-4

InChI key

CKLBXIYTBHXJEH-UHFFFAOYSA-J

Related Categories

General description

Alcian blue is a large conjugated dye molecule, and comprises of a central copper-containing pthalocyanine ring linked to four isothiouronium groups via thioether bonds. The isothiouronium groups are responsible for the cationic nature of alcian blue owing to them being moderately strong bases. It was initially used in dyeing of textile fibres. Alcian blue 8GX is a dye recommended normally for histological technique.

Application

Alcianblue 8GX solution has been used as a staining dye for chondrocytic, osteoblastic and adipocytic differentiation. It has also been used for the staining of sections in immunohistochemistry.

Analysis Note

1% solution in 3% acetic acid

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

66011-500ML-F:4548173923017
66011-VAR:
66011-VAR-F:
66011-BULK:
66011-BULK-F:
66011-100ML-F:4548173923000

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL9242
BCCK5618
BCCG7004
BCCC8957
BCCB4703

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John D. Bancroft
Theory and Practice of Histological Techniques, 172-172 (2008)
Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.
Hirao M et al.
The Journal of Biological Chemistry, 281, 31079-31079 (2006)
Yong Mao et al.
Acta biomaterialia, 85, 75-83 (2018-12-12)
A significant expansion of autologous chondrocytes in vitro is required for cell-based cartilage repair. However, the in vitro expansion of chondrocytes under standard culture conditions inevitably leads to the dedifferentiation of chondrocytes and contributes to suboptimal clinical outcomes. To address
Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.
Cammareri P et al.
Cancer Research, 70, 4655-4655 (2010)

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