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Safety Information

901767

Sigma-Aldrich

PC biotin-PEG3-NHS ester

Synonym(s):

PC biotin-NHS ester

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About This Item

Empirical Formula (Hill Notation):
C36H52N6O15S
CAS Number:
2353409-93-3
Molecular Weight:
840.89
MDL number:
MFCD31811520
UNSPSC Code:
51171641
NACRES:
NA.22

form

solid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

mp

170 °C

storage temp.

−20°C

SMILES string

S1[C@H]([C@H]4NC(=O)N[C@H]4C1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCCOc2c(cc(c(c2)[N+](=O)[O-])C(OC(=O)ON3C(=O)CCC3=O)C)OC

InChI

1S/C36H52N6O15S/c1-23(56-36(48)57-41-32(45)9-10-33(41)46)24-20-27(51-2)28(21-26(24)42(49)50)55-13-5-8-31(44)38-12-15-53-17-19-54-18-16-52-14-11-37-30(43)7-4-3-6-29-34-25(22-58-29)39-35(47)40-34/h20-21,23,25,29,34H,3-19,22H2,1-2H3,(H,37,43)(H,38,44)(H2,39,

InChI key

WXAMRLAFOFNACR-VTJXTUSFSA-N

Application

PC biotin-NHS ester is a unique amine-reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

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related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

901767-BULK:
901767-25MG:
901767-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW6727
MKCV8589
MKCS5656
MKCQ1420
MKCL9445

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Articles

Crosslinkers Selection Guide

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