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Safety Information

G0750

Sigma-Aldrich

D-(+)-Galactose

≥99% (HPLC)

Synonym(s):

Galactose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
59-23-4
Molecular Weight:
180.16
Beilstein:
1724619
EC Number:
200-416-4
MDL number:
MFCD00151230
UNSPSC Code:
12352201
PubChem Substance ID:
24895021
NACRES:
NA.21

biological source

bovine (Ruminant- Cow, Ox, Buffalo)

Quality Level

300

Assay

≥99% (HPLC)

form

powder

technique(s)

HPLC: suitable

impurities

≤0.1% glucose

color

white

useful pH range

5.0-7 (25 °C, 180 g/L)

mp

168-170 °C (lit.)

solubility

H2O: soluble 100 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1

InChI key

GZCGUPFRVQAUEE-KCDKBNATSA-N

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Application

Galactose has been used:
  • as a component of galactosyltransferase labeling buffer.
  • as a supplement in MRS broth for the growth of thermophilic lactobacilli
  • to induce the expression of uncoupling protein (UCP) in yeast transformants

Biochem/physiol Actions

Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

G0750-BULK:
G0750-50G:4548173217345
G0750-100G:4548173217291
QG0750-VAR:
G0750-VAR:
G0750-10G:4548173217307
G0750-25G:4548173217321
G0750-1KG:4548173217314
G0750-5G-KC:
QG0750-BULK:
G0750-RSAMPLE:
G0750-5G:4548173217352
G0750-500G:4548173217338
G0750-10MG:

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF3331V
BCCM4101
WXBF4480V
WXBF3756V
BCCL4154

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K W Turner et al.
Applied and environmental microbiology, 45(6), 1932-1934 (1983-06-01)
The ability to ferment galactose is a major characteristic which can be used to differentiate Lactobacillus helveticus (galactose positive) from Lactobacillus lactis and Lactobacillus bulgaricus (galactose negative). In milk cultures, galactose-positive strains produced d- and l-lactic acid with little galactose
D L Murdza-Inglis et al.
The Journal of biological chemistry, 269(10), 7435-7438 (1994-03-11)
The uncoupling protein is one of a family of mitochondrial transport proteins involved in energy metabolism. It dissipates oxidative energy to generate heat, either by catalyzing proton transport directly or by catalyzing fatty acid anion transport, thus enabling fatty acids
Zu-Hong He et al.
Redox biology, 28, 101364-101364 (2019-11-16)
Inflammation is a self-defense response to protect individuals from infection and tissue damage, but excessive or persistent inflammation can have adverse effects on cell survival. Many individuals become especially susceptible to chronic-inflammation-induced sensorineural hearing loss as they age, but the
Inge E Krabbendam et al.
Cell death & disease, 11(4), 263-263 (2020-04-25)
Metabolic flexibility is an essential characteristic of eukaryotic cells in order to adapt to physiological and environmental changes. Especially in mammalian cells, the metabolic switch from mitochondrial respiration to aerobic glycolysis provides flexibility to sustain cellular energy in pathophysiological conditions.
Hwa-Young Lee et al.
Redox biology, 37, 101727-101727 (2020-10-04)
Oxidative stress attributable to the activation of a Nox4-containing NADPH oxidase is involved in aging-associated vascular dysfunction. However, the Nox4-induced signaling mechanism for the vascular alteration in aging remains unclear. In an aged aorta, the expression of Nox4 mRNA and
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