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Safety Information

NIST971A

Hormones in Frozen Human Serum

NIST®SRM®

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About This Item

UNSPSC Code:
41116107
NACRES:
NA.24

packaging

pkg of 4.08 g

manufacturer/tradename

NIST®

technique(s)

mass spectrometry (MS): suitable

application(s)

clinical testing

storage temp.

−70°C

General description

A unit of Hormones in Frozen Human Serum standard reference material (SRM) consists of two vials each of two materials: one from a pool of healthy, premenopausal adult females and one from a pool of healthy adult males. The certified values of the SRM were determined using higher-order reference measurement procedures calibrated with high-purity chemical reference standards in combination with higher-order measurement procedures conducted by the CDC. The uncertainties are expanded uncertainties at the 95 % level of confidence. The certified values of the SRM, apply only to serum thawed to room temperature, 20 °C to 25 °C.

SRM 971a_cert

SRM 971a _SDS

Application

ThisNIST SRM 971a is intended primarily for use in evaluating the accuracy of procedures for the determination of the steroid hormones cortisol, progesterone, and testosterone, and thyroid hormones total thyroxine (T4), and total 3,3′,5-triiodothyronine (T3) in human serum.
It is also intended for use in validating working or secondary reference materials.

Features and Benefits

  • A unit of SRM contains two vials of each material. Each vial approximately contains 2 mL of human serum
  • Both materials in the SRM are unfortified

Other Notes

  • SRM 971a is intended for research use.
  • The serum is shipped frozen (on dry ice) and, upon receipt, should be stored frozen until ready for use.
  • Expiration details and storage and use instructions are provided on the NIST certificate
  • Notes on biomaterial handling, disposal, and transport documented in MSDS

Legal Information

NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

NIST971:
NIST971A:

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Certificates of Analysis (COA)

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Sung-Eun Cho et al.
Annals of laboratory medicine, 43(1), 19-28 (2022-09-01)
Mass spectrometry methods exhibit higher accuracy and lower variability than immunoassays at low testosterone concentrations. We developed and validated an ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) assay for quantifying serum total testosterone. We used an ExionLC UPLC (Sciex, Framingham, MA
Nyasha Munjoma et al.
Journal of proteome research, 21(11), 2596-2608 (2022-10-21)
Lipids play a key role in many biological processes, and their accurate measurement is critical to unraveling the biology of diseases and human health. A high throughput HILIC-based (LC-MS) method for the semiquantitative screening of over 2000 lipids, based on

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