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Y0000012

Hymecromone impurity A

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Resorcinol, 1,3-Benzenediol

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About This Item

Linear Formula:
C6H4-1,3-(OH)2
CAS Number:
108-46-3
Molecular Weight:
110.11
Beilstein:
906905
MDL number:
MFCD00002269
UNSPSC Code:
41116107
PubChem Substance ID:
329830814
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

3.8 (vs air)

vapor pressure

1 mmHg ( 21.1 °C)

API family

hymecromone

autoignition temp.

1126 °F

manufacturer/tradename

EDQM

bp

178 °C/16 mmHg (lit.)

mp

109-112 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Oc1cccc(O)c1

InChI

1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H

InChI key

GHMLBKRAJCXXBS-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hymecromone impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 1 Oral - STOT SE 2 Oral

Target Organs

Central nervous system,Blood, Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

260.6 °F - closed cup

Flash Point(C)

127 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

Y0000012-1EA:
Y0000012:

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Lot/Batch Number

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Barry S Lynch et al.
Regulatory toxicology and pharmacology : RTP, 36(2), 198-210 (2002-12-04)
Resorcinol administered at high doses to rodents can disrupt thyroid hormone synthesis and can produce goitrogenic effects. These effects were not seen in a 2-year bioassay at doses of up to 520 mg/kg/day. There are species-specific differences in synthesis, binding
Ahmed M Elkhatat et al.
Advanced materials (Deerfield Beach, Fla.), 23(26), 2887-2903 (2011-05-25)
An overview on the preparation and properties of resorcinol-formaldehyde (RF) organic and carbon gels reveals the fascinating and remarkably flexible properties of RF carbon and organic gels and how these properties are related to the synthesis and processing conditions. The
50% resorcinol peel.
P G Karam
International journal of dermatology, 32(8), 569-574 (1993-08-01)
Resorcinol.
IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 3, 1119-1131 (1999-09-07)
Frank Welsch
International journal of toxicology, 27(1), 59-63 (2008-02-23)
Medical case reports published in the 20th century over the course of several decades show that resorcinol caused reversible adverse effects on the human thyroid gland (TG) manifested as hypothyroidism. Affected patients had ulcerating leg varicosities and underwent prolonged treatment
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