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319902

Sigma-Aldrich

Ethyl acetate

ACS reagent, ≥99.5%

Synonym(s):

EtOAc

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About This Item

Linear Formula:
CH3COOC2H5
CAS Number:
141-78-6
Molecular Weight:
88.11
Beilstein:
506104
EC Number:
205-500-4
MDL number:
MFCD00009171
UNSPSC Code:
12352108
PubChem Substance ID:
329753937
NACRES:
NA.21
grade:
ACS reagent
Assay:
≥99.5%
bp:
76.5-77.5 °C (lit.)
vapor pressure:
73 mmHg ( 20 °C)

grade

ACS reagent

Quality Level

200

Agency

suitable for EPA ACB B21-02
suitable for EPA ACB B23-05b

vapor density

3 (20 °C, vs air)

vapor pressure

73 mmHg ( 20 °C)

Assay

≥99.5%

form

liquid

autoignition temp.

801 °F

expl. lim.

2.2-11.5 %, 38 °F

impurities

H2SO4, passes test (darkened)
≤0.0009 meq/g Titr. acid
≤0.200% water

evapn. residue

≤0.0030%

color

APHA: ≤10

refractive index

n20/D 1.3720 (lit.)

bp

76.5-77.5 °C (lit.)

mp

−84 °C (lit.)

density

0.902 g/mL at 25 °C (lit.)

format

neat

SMILES string

CCOC(C)=O

InChI

1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3

InChI key

XEKOWRVHYACXOJ-UHFFFAOYSA-N

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General description

Ethyl acetate ACS grade solvent meets or exceeds the high standards of the American Chemical Society (ACS). It is ideal for most research needs and delivers replicable, publishable results.
Ethyl acetate ACS grade solvent used in:      
  • Routine chemical synthesis      
  • Drying & purification     
  • Critical labware cleaning

Application

Ethyl acetate (ACS grade) can be used as a solvent in the synthesis of 6-O-acetyl glycosides via selective acetylation of carbohydrates in the presence of a catalytic amount of sulfuric acid. 6-O-acetyl glycoside derivatives are applicable as precursors for the synthesis of complex oligosaccharides.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319,H336

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

EUH066

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

24.8 °F - closed cup

Flash Point(C)

-4 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

319902-4X2L:4548173256368
319902-18L:4548173256351
319902-200L-PW:
319902-BULK:
319902-2.5L:4548173317878
319902-4X4L-PB:
319902-4L:4548173134093
319902-VAR:
319902-4X4L:4548173134109
319902-200L-P2:
319902-1L:4548173134055
319902-18L-CS:
319902-500ML:4548173134116
319902-6X1L:4548173256375
319902-200L:4548173134062
319902-6X500ML:4548173256382
319902-2L:4548173134086
319902-20L:4548173134079
319902-VAR-D:
319902-7L-PW:
319902-25ML:
319902-18L-P1-BL:

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Certificates of Analysis (COA)

Lot/Batch Number
SHBR8880
SHBR7305
STBL4509
STBL4421
STBL3812

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A green and regioselective acetylation of thioglycoside with ethyl acetate
Liang Pi-Hui, et al.
Tetrahedron Letters, 51(52), 6928-6931 (2010)
Elif Burcu Bali et al.
Asian Pacific journal of tropical biomedicine, 4(7), 505-514 (2014-09-04)
To investigate the in vitro antimicrobial potential of Thermopsis turcica Kit Tan, Vural & Küçüködük against periodontopathogenic bacteria, its antioxidant activity and cytotoxic effect on various cancer cell lines. In vitro antimicrobial activities of ethanol, methanol, ethyl acetate (EtAc), n-hexane
Quinn P Peterson et al.
Nature protocols, 5(2), 294-302 (2010-02-06)
This protocol describes the gram-scale solution-phase synthesis of the colorimetric caspase-3/7 substrate Ac-DEVD-pNA. The caspase enzymes are integral to cellular inflammation and apoptotic cascades, and are commonly studied by cell biologists, medicinal chemists and chemical biologists. In particular, the assessment
Chayasith Uttamapinant et al.
Nature protocols, 8(8), 1620-1634 (2013-07-28)
This protocol describes an efficient method to site-specifically label cell-surface or purified proteins with chemical probes in two steps: probe incorporation mediated by enzymes (PRIME) followed by chelation-assisted copper-catalyzed azide-alkyne cycloaddition (CuAAC). In the PRIME step, Escherichia coli lipoic acid
Libo Zhou et al.
Journal of visualized experiments : JoVE, (159) (2020-05-26)
A biomimetic NM was developed to serve as a tissue-engineering biological scaffold, which can enhance stem cell anchorage. The biomimetic NM is formed from JBNTs and FN through self-assembly in an aqueous solution. JBNTs measure 200-300 µm in length with
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