Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

Safety Information

319953

Sigma-Aldrich

Benzene

ACS reagent, ≥99.0%

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C6H6
CAS Number:
71-43-2
Molecular Weight:
78.11
Beilstein:
969212
EC Number:
200-753-7
MDL number:
MFCD00003009
UNSPSC Code:
12352002
PubChem Substance ID:
329753940
NACRES:
NA.21

grade

ACS reagent

Quality Level

200

vapor density

2.77 (vs air)

vapor pressure

166 mmHg ( 37.7 °C)
74.6 mmHg ( 20 °C)

Assay

≥99.0%

form

liquid

autoignition temp.

1043 °F

expl. lim.

8 %

impurities

H2SO4, passes test (darkened)
 thiophene, passes test (limit ∼1ppm)
≤0.005% S compounds
≤0.05% water (Karl Fischer)

evapn. residue

≤0.001%

color

APHA: ≤10

refractive index

n20/D 1.501 (lit.)

bp

80 °C (lit.)

mp

5.5 °C (lit.)

density

0.874 g/mL at 25 °C (lit.)

SMILES string

c1ccccc1

InChI

1S/C6H6/c1-2-4-6-5-3-1/h1-6H

InChI key

UHOVQNZJYSORNB-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Benzene is a monocyclic aromatic compound used as a solvent in chemical reactions. It is an essential raw material for fuels, rubber and plastics products, detergents, pesticides, and pharmaceuticals.

Application

Benzene can be used as a solvent in the:
  • Heck Reaction of vinyl bromides with styrenes to synthesize functionalized 1,3-dienes.
  • Gallium-catalyzed reductive lactonization of γ-keto acids to γ-lactone derivatives.
  • Anionic polymerization of styrene and 1,3-butadiene in the presence of phosphazene as a base.

Signal Word

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 1A - Eye Irrit. 2 - Flam. Liq. 2 - Muta. 1B - Skin Irrit. 2 - STOT RE 1

Target Organs

Blood

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

12.2 °F

Flash Point(C)

-11 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Specified Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

319953-1L:4548173134314
319953-2.5L:
319953-2L:4548173134338
319953-VAR:
319953-4L:
319953-500ML:4548173134352
319953-BULK:
319953-4X2L:4548173256450
319953-20L:4548173134321
319953-18L:4548173256443
319953-4X4L:4548173134345

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

David Galbraith et al.
Critical reviews in toxicology, 40 Suppl 2, 1-46 (2010-10-14)
Over the last century, benzene has been a well-studied chemical, with some acute and chronic exposures being directly associated with observed hematologic effects in humans and animals. Chronic heavy exposures to benzene have also been associated with acute myelogenous leukemia
Audrey Smargiassi et al.
Environmental research, 132, 38-45 (2014-04-20)
The acute cardiorespiratory effects of air quality among children living in areas with considerable heavy industry have not been well investigated. We conducted a panel study of children with asthma living in proximity to an industrial complex housing two refineries
César C Martins et al.
Environmental pollution (Barking, Essex : 1987), 188, 71-80 (2014-02-22)
Babitonga Bay is a South Atlantic estuary with significant ecological function; it is part of the last remaining areas of mangrove communities in the Southern Hemisphere. The aim of this study was to determine the spatial distribution of the faecal
Cliona M McHale et al.
Carcinogenesis, 33(2), 240-252 (2011-12-15)
Benzene causes acute myeloid leukemia and probably other hematological malignancies. As benzene also causes hematotoxicity even in workers exposed to levels below the US permissible occupational exposure limit of 1 part per million, further assessment of the health risks associated
Jelle Vlaanderen et al.
Environmental health perspectives, 119(2), 159-167 (2010-10-01)
The use of occupational cohort studies to assess the association of benzene and lymphoma is complicated by problems with exposure misclassification, outcome classification, and low statistical power. We performed meta-analyses of occupational cohort studies for five different lymphoma categories: Hodgkin
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service