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Safety Information

C7631

Sigma-Aldrich

Copper(II) sulfate pentahydrate

ReagentPlus®, ≥98.0%

Synonym(s):

Cupric sulfate pentahydrate, Sulfuric acid, copper(II) salt (1:1) pentahydrate

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About This Item

Linear Formula:
CuSO4 · 5H2O
CAS Number:
7758-99-8
Molecular Weight:
249.69
EC Number:
231-847-6
MDL number:
MFCD00149681
UNSPSC Code:
12352302
PubChem Substance ID:
329775147
NACRES:
NA.21
Assay:
≥98.0%
form:
powder or crystals

vapor pressure

7.3 mmHg ( 25 °C)

Quality Level

100

product line

ReagentPlus®

Assay

≥98.0%

form

powder or crystals

pH

3.7-4.5 (25 °C, 50 g/L)

mp

110 °C (dec.) (lit.)

cation traces

Fe: ≤0.01%

SMILES string

O.O.O.O.O.[Cu++].[O-]S([O-])(=O)=O

InChI

1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2

InChI key

JZCCFEFSEZPSOG-UHFFFAOYSA-L

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General description

Copper(II) sulfate is an inorganic Lewis acid commonly used to promote acid?catalyzed organic reactions. It is used as a reagent for the synthesis of copper carbenoids. It can also act as an effective redox catalyst in combination with other mixed oxidizing systems.

Application


  • Determination of main fruits in adulterated nectars by ATR-FTIR spectroscopy combined with multivariate calibration and variable selection methods.: This study highlights the application of ATR-FTIR spectroscopy, a technique involving Copper(II) sulfate pentahydrate, in identifying fruit content in adulterated nectars, illustrating its relevance in food chemistry and quality control (de Souza SVC et al., 2018).

  • Measurement of electron paramagnetic resonance using terahertz time-domain spectroscopy.: This research demonstrates the use of terahertz time-domain spectroscopy, involving Copper(II) sulfate pentahydrate, to measure electron paramagnetic resonance, contributing to advancements in spectroscopic methodologies (Hangyo M et al., 2011).

  • Effects of Curcuma xanthorrhiza Extracts and Their Constituents on Phase II Drug-metabolizing Enzymes Activity.: Though indirectly related, this article explores the role of natural extracts on enzyme activity, providing a context where Copper(II) sulfate pentahydrate could be used as a comparative standard in bioanalytical settings (Ab Halim MR et al., 2016).


Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Hazard Statements

H302,H318,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

C7631-1KG:4548173192260
C7631-500G:4548173192284
C7631-VAR:
2530146:
2003280:
C7631-BULK:
C7631-250G:4548173192277

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR7508
0000333916
MKCW5154
MKCW9155
MKCT8965

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Copper(II) Sulfate
Encyclopedia of Reagents for Organic Synthesis, Second Edition (2016)
Bárbara Acosta-Iborra et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(5), 6654-6674 (2020-03-31)
Angiogenesis, the main mechanism that allows vascular expansion for tissue regeneration or disease progression, is often triggered by an imbalance between oxygen consumption and demand. Here, by analyzing changes in the transcriptomic profile of endothelial cells (ECs) under hypoxia we
Bhagwan S Batule et al.
International journal of nanomedicine, 10 Spec Iss, 137-142 (2015-09-09)
We developed a simple but efficient method to synthesize protein-inorganic hybrid nanostructures with a flower-like shape (nanoflowers), which relies on sonication to facilitate the synthesis of the nanoflowers. With this technique, we synthesized nanoflowers containing laccase as a model protein
Gabriela M B Haverroth et al.
Ecotoxicology and environmental safety, 122, 440-447 (2015-09-20)
Copper is a heavy metal found at relatively high concentrations in surface waters around the world. Copper is a micronutrient at low concentrations and is essential to several organisms. At higher concentrations copper can become toxic, which reveal the importance
Yuan Chen et al.
Biochemical and biophysical research communications, 459(3), 529-533 (2015-03-10)
Apolipoprotein E (ApoE) genotypes are related to clinical presentations in patients with Wilson's disease, indicating that ApoE may play an important role in the disease. However, our understanding of the role of ApoE in Wilson's disease is limited. High copper
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