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Safety Information

17348

Sigma-Aldrich

2-Hydroxyethyl methacrylate

embedding medium (for microscopy)

Synonym(s):

1,2-Ethanediol mono(2-methylpropenoate), Glycol methacrylate, HEMA

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About This Item

Linear Formula:
CH2=C(CH3)COOCH2CH2OH
CAS Number:
868-77-9
Molecular Weight:
130.14
Beilstein:
1071583
EC Number:
212-782-2
MDL number:
MFCD00002863
UNSPSC Code:
12162002
PubChem Substance ID:
57647639
NACRES:
NA.25

grade

embedding medium (for microscopy)

Quality Level

100

vapor density

5 (vs air)

vapor pressure

0.01 mmHg ( 25 °C)

Assay

≥99%

form

liquid

contains

~0.001% hydroquinone monomethyl ether as stabilizer

impurities

<250 mg/kg free acid (as methycrylic acid) (T)

refractive index

n20/D 1.453 (lit.)
n20/D 1.453

bp

67 °C/3.5 mmHg (lit.)

density

1.071 g/mL at 20 °C
1.073 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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Application

2-Hydroxyethyl methacrylate has been used in a study to describe a novel methodology for grafting polymers via radical photopolymerization initiated on gold surfaces by aryl layers from diazonium salt precursors. 2-Hydroxyethyl methacrylate has also been used in a study to provide insight into the induction of apoptosis and the differential expression of antioxidant enzymes depending on the availability of glutathione.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

222.8 °F - closed cup

Flash Point(C)

106 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

17348-BULK-F:
17348-250ML-F:
17348-VAR-F:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM6015
BCCL2043
BCCK5878
BCCJ5506
BCCG9336

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Sarra Gam-Derouich et al.
Langmuir : the ACS journal of surfaces and colloids, 28(21), 8035-8045 (2012-05-03)
In this paper we describe a novel methodology for grafting polymers via radical photopolymerization initiated on gold surfaces by aryl layers from diazonium salt precursors. The parent 4-(dimethylamino)benzenediazonium salt was electroreduced on a gold surface to provide 4-(dimethylamino)phenyl (DMA) hydrogen
Stephanie Krifka et al.
Biomaterials, 33(21), 5177-5186 (2012-04-27)
Resin monomers like 2-hydroxyethyl methacrylate (HEMA) disturb cell functions including responses of the innate immune system, mineralization and differentiation, or induce cell death via apoptosis. These phenomena are associated with oxidative stress and a reduction in the concentration of the
Brendan P Purcell et al.
Biomaterials, 33(31), 7849-7857 (2012-07-28)
Poor cell engraftment in the myocardium is a limiting factor towards the use of bone marrow derived cells (BMCs) to treat myocardial infarction (MI). In order to enhance the engraftment of circulating BMCs in the myocardium following MI, we have
Duncan Chege et al.
Journal of acquired immune deficiency syndromes (1999), 65(5), 517-525 (2013-11-22)
To evaluate if systemic murine malarial infection enhances HIV susceptibility through parasite-induced mucosal immune alterations at sites of HIV sexual exposure. Malaria and HIV have a high degree of geographical overlap and interact substantially within coinfected individuals. We used a
M Bourbia et al.
Journal of dental research, 92(11), 989-994 (2013-09-13)
A major reason for dental resin composite restoration replacement is related to secondary caries promoted by acid production from bacteria including Streptococcus mutans (S. mutans). We hypothesized that S. mutans has esterase activities that degrade dental resin composites and adhesives.
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