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Safety Information

C7263

Sigma-Aldrich

Calcium phosphate dibasic

98.0-105.0%

Synonym(s):

Calcium hydrogen phosphate

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About This Item

Linear Formula:
CaHPO4
CAS Number:
7757-93-9
Molecular Weight:
136.06
EC Number:
231-826-1
MDL number:
MFCD00010909
UNSPSC Code:
12161700
PubChem Substance ID:
24892950
NACRES:
NA.25

Quality Level

100

Assay

98.0-105.0%

form

powder

SMILES string

[Ca++].OP([O-])([O-])=O

InChI

1S/Ca.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+2;/p-2

InChI key

FUFJGUQYACFECW-UHFFFAOYSA-L

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Application

Calcium phosphate dibasic has been used:
  • to prepare high temperature stoichiometric sintered hydroxyapatite (sin-HA)
  • as a component of calcium phosphate cement (CPC) to prepare bioartificial pancreas (BAP)
  • to produce calcium pyrophosphate (Ca2P2O7) for the preparation of α-tricalcium phosphates (α-TCP)

Biochem/physiol Actions

Calcium phosphate dibasic is an anhydrate used to dilute tablets and capsules. It is widely used as an excipient for its compressibility, amenability, and brittle fracture propensity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C7263-VAR:
C7263-500G:
C7263-100G:
C7263-BULK:
C7263-2.5KG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anna Diez-Escudero et al.
Tissue engineering. Part C, Methods, 23(2), 118-124 (2017-01-14)
This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging technique is able to reveal microstructural changes at a level of
Kai-Chiang Yang et al.
Transplantation, 90(6), 604-611 (2010-01-06)
Fibrous tissue outgrowth and hypoxia are the major restrictions for the application of bioartificial pancreas (BAP). Accordingly, the intramedullary cavity is proposed as an implant site, and a BAP constructed of calcium phosphate cement chamber was implanted. Mouse insulinoma cells
Aditya M Kaushal et al.
Journal of pharmaceutical sciences, 100(4), 1456-1466 (2011-04-01)
Dibasic calcium phosphate occurs as an anhydrate (DCPA; CaHPO₄) and as a dihydrate (DCPD; CaHPO₄•2H₂O). Our objective was to investigate the unusual behavior of these phases. Dibasic calcium phosphate dihydrate was dehydrated in a (i) differential scanning calorimeter (DSC) in
C L Camiré et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 79(1), 159-165 (2006-04-15)
Alpha phase tricalcium phosphates (alpha-TCP) were produced using a solid-state reaction method and milled for various periods of time. The resulting four materials were alpha-TCPs, ranging in crystalline content. Powders were exposed to X-ray diffraction for material identification as well
Tae-Woo Kim et al.
Tissue engineering and regenerative medicine, 17(5), 607-624 (2020-08-18)
The delivery of growth factors using a carrier system presents a promising and innovative tool in tissue engineering and dentistry today. Two of the foremost bioactive factors, bone morphogenetic protein-2 and vascular endothelial growth factor (VEGF), are widely applied using
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