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Safety Information

N0505

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate

Synonym(s):

Triphosphopyridine nucleotide sodium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C21H27N7NaO17P3 · xH2O
CAS Number:
698999-85-8
Molecular Weight:
765.39 (anhydrous basis)
MDL number:
MFCD00150480
UNSPSC Code:
41106305
PubChem Substance ID:
24897427
NACRES:
NA.51

biological source

chicken liver

Quality Level

300

Assay

≥98% (HPLC)
≥98% (spectrophotometric assay)

form

powder

mp

175-178 °C (dec.) (lit.)

solubility

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(OP(OC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](OP(O)(O)=O)[C@@H]3O)([O-])=O)([O-])=O.O.[Na+]

InChI

1S/C21H28N7O17P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1

InChI key

CYQLUFJYVTUUFN-WUEGHLCSSA-M

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Related Categories

Biochem/physiol Actions

Electron acceptor

Packaging

Packaged by solid weight.

Other Notes

This is the common form of NADP. Do not confuse with 3′−NADP or α-NADP.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

2540048:
N0505PROC:
N0505-CP:
N0505-BULK:
N0505-1G-C:
N0505-500MG:4548174008874
N0505-50MG:
N0505-5G-C:
N0505-1G:4548174008867
N0505-VAR:
N0505-100MG:4548174008850
N0505-5G:4548174008881
N0505-PM:
N0505-25MG:

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Certificates of Analysis (COA)

Lot/Batch Number
0000361371
0000387629
0000364233
0000364228
0000364156

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Syaghalirwa N M Mandiki et al.
Steroids, 70(2), 85-94 (2005-01-06)
Sex steroid inhibitors were used to characterize the effects of 17beta-estradiol (E2) and testosterone (T) on the sexual growth dimorphism of Eurasian perch juveniles. In experiment 1, growth responses to different doses of either E2 (25, 50, 75, and 100
F Moreno et al.
European journal of biochemistry, 161(3), 565-569 (1986-12-15)
Hexokinase PII is not inhibited by high Mg-ATP concentrations if the Mg2+-free ATP is kept at low levels (0.01 mM) in the assay mixture. Hexokinase PI activity is not affected either by Mg2+-free ATP nor by free Mg2+ in the
David J Waxman et al.
Methods in molecular biology (Clifton, N.J.), 320, 91-96 (2006-05-25)
A spectrofluorometric method is described for the determination of CYP2A6-catalyzed coumarin 7-hydroxylation. Following acidification of the reaction mixture, the enzymatic product, 7-hydroxycoumarin, is recovered by a double-extraction procedure and assayed using an excitation wavelength of 370 nm and an emission
Jianneng Li et al.
Science translational medicine, 13(595) (2021-05-28)
Prostate cancer resistance to next-generation hormonal treatment with enzalutamide is a major problem and eventuates into disease lethality. Biologically active glucocorticoids that stimulate glucocorticoid receptor (GR) have an 11β-OH moiety, and resistant tumors exhibit loss of 11β-HSD2, the oxidative (11β-OH
Considine, DM et al.
Van Nostrand Reinhold Encyclopedia of Chemistry, 1993-1993 null
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Protocols

Enzymatic Assay of Hexokinase

Measure hexokinase activity using a continuous spectrophotometric rate-determination assay at 340 nm, catalyzing D-hexose sugar phosphorylation using ATP.

Enzymatic Assay of Glucose-6-Phosphate Dehydrogenase (EC 1.1.1.49)

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

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