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O5632

Sigma-Aldrich

Linoleic acid, conjugated methyl ester

Synonym(s):

CLA methyl ester, Octadecadienoic acid, conjugated, methyl ester

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

biological source

plant (safflower)

Quality Level

100

Assay

≥99% (GC)

form

liquid

technique(s)

GC/MS: suitable
HPLC: suitable

impurities

≤1% Linoleic acid methyl ester

functional group

carboxylic acid
ester

lipid type

omega FAs

shipped in

ambient

storage temp.

−20°C

Related Categories

General description

Conjugated linoleic acid (CLA) describes the positional and geometric isomers of C18:2 fatty acids (FA) with a conjugated double bond. cis-9, trans-11 CLA are considered as the major isomers of CLA, based on in vitro experiments and animal studies in milk. The major source of CLA in human diet is the ruminant fat.

Application

Linoleic acid, conjugated methyl ester (CLA) has been used as a standard for the determination of isomers of CLA in milk samples by high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry. It has also been used in the production of sn-1,3 diacyl glycerol.

Biochem/physiol Actions

Conjugated linoleic acid (CLA) isomers as supplements inhibit the growth of numerous human cancer cell lines. It also possesses immunostimulant properties, prevents diabetes and reduces atherosclerosis.

Other Notes

A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acid methyl esters. Isomer ratio may vary from lot to lot.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

O5632-BULK:
O5632-250MG:
O5632-1G:
O5632-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV7882
MKCT2649
MKCQ4218
MKCP6901
MKCN7071

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M Coppa et al.
Journal of dairy science, 102(11), 10483-10499 (2019-09-10)
The aims of this work were to determine the effect of upland origin on milk composition when comparing similar lowland and upland production system and to highlight the factors responsible for the added value of upland milk from commercial farms.
P G Toral et al.
Journal of dairy science, 101(7), 6109-6121 (2018-05-01)
A great deal of uncertainty still exists about intermediate metabolites and pathways explaining the biohydrogenation (BH) of 20- and 22-carbon polyunsaturated fatty acids (PUFA). Therefore, this study was conducted to provide further insight into the ruminal metabolism of 20:5 n-3
A D Martin et al.
Journal of dairy science, 98(8), 5374-5384 (2015-05-26)
To investigate the feasibility of milk fatty acids as predictors of onset of luteal activity (OLA), 87 lactations taken from 73 healthy Norwegian Red cattle were surveyed over 2 winter housing seasons. The feasibility of using frozen milk samples for
A Bougouin et al.
Journal of dairy science, 101(7), 6085-6097 (2018-04-24)
The aim of the study was to compare the effect of fiber- or starch-rich diets based on grass silage, supplemented or not with bicarbonate, on CH4 emissions and milk fatty acid (FA) profile in dairy cows. The experiment was conducted
Examination of the persistency of milk fatty acid composition responses to fish oil and sunflower oil in the diet of dairy cows
Shingfield KJ, et al.
Journal of Dairy Science, 89(2), 714-732 (2006)
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