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Safety Information

P1504

Sigma-Aldrich

TWEEN® 40

viscous liquid

Synonym(s):

Polyoxyethylenesorbitan monopalmitate

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About This Item

CAS Number:
9005-66-7
MDL number:
MFCD00165345
UNSPSC Code:
12161900
NACRES:
NA.25

description

non-ionic

Quality Level

200

Assay

~90.0% (GC)

form

viscous liquid

mol wt

estimated mol wt 1277

composition

Palmitic acid, ~90% (balance primarily stearic acid)

technique(s)

DNA extraction: suitable
RNA extraction: suitable
cell culture | mammalian: suitable
protein purification: suitable

CMC

0.027 (20-25°C)

HLB

15.6

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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General description

Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, is a non-ionic detergent.

Application

Non-ionic detergent used for cell lysis, nuclei isolation and cell fractionation.
Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, has been used in a study to assess the determination of iodide in urine based on a chemiluminescence system. It has also been used in a study to investigate the delivery of astaxanthin and canthaxanthin to HepG2 cells.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

P1504-1GA:
P1504-VAR:
P1504-100ML:
P1504-500ML:
P1504-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christine Boesch-Saadatmandi et al.
Cytotechnology, 63(1), 89-97 (2010-12-15)
The present investigation aimed to compare fetal calf serum (FCS) and Tween 40 with the commonly employed tetrahydrofuran (THF) with respect to cytotoxicity, stability of the solubilized carotenoids, and uptake and accumulation of the xanthophylls astaxanthin (AX) and canthaxanthin (CX)
Mohammad Reza Lornejad-Schäfer et al.
European journal of nutrition, 46(2), 79-86 (2007-01-18)
Carotenoids lutein and zeaxanthin are proposed to protect ocular tissues from free-radical damage that can cause cataract and age-related macular degeneration (AMD). They accumulate selectively in the lens and macular region of the retina. Changes in the retinal pigment epithelium
Takamasa Kaneko et al.
Medical mycology, 44(3), 227-231 (2006-05-17)
We developed a simple identification kit for nine species of Malassezia (M. furfur, M. slooffiae, M. sympodialis, M. restricta, M. obtusa, M. globosa, M. pachydermatis, M. dermatis, and M. japonica) based on their biological features. This method utilizes Tween 40-based
Sinead M O'Sullivan et al.
The British journal of nutrition, 91(5), 757-764 (2004-05-13)
Epidemiological evidence suggests that dietary intake of carotenoids and tocopherols may influence the risk of certain chronic diseases, such as cancer and CVD. In vitro studies investigating the synergistic effects of mixtures of carotenoids and tocopherols have been hindered due
Branka Rozman et al.
Drug delivery, 14(4), 235-245 (2007-05-15)
An interesting strategy for protecting skin from excessive exposure to free radicals is to support the skin endogenous antioxidant system. As the balance between different skin antioxidants is very important, a combined therapy using at least two antioxidants is desirable.
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