Skip to Content
Merck
All Photos(3)

Key Documents

Safety Information

P1750

Sigma-Aldrich

Pancreatin from porcine pancreas

4 × USP specifications

Synonym(s):

Pancreatin from hog pancreas

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

CAS Number:
8049-47-6
EC Number:
232-468-9
MDL number:
MFCD00131789
UNSPSC Code:
12352204
NACRES:
NA.54

Agency

USP (specifications)

Quality Level

200

form

powder

specific activity

4 × USP specifications

contains

lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Pancreatin from porcine pancreas has been used:
  • for a study to assess the treatment of steatorrhea by lipase supplementation therapy
  • for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis
  • to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity
  • to assess cleavage by digestive enzymes.
  • for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors.
  • along with amyloglucosidase for the in vitro digestion of starch in food samples.

Biochem/physiol Actions

Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H317,H319,H334,H335

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

P1750-500G:
P1750-100G:
P1750-VAR:
P1750-25G:
P1750-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

David C Whitcomb et al.
Digestive diseases and sciences, 52(1), 1-17 (2007-01-06)
A primary function of the pancreas is to produce digestive enzymes that are delivered to the small intestine for the hydrolysis of complex nutrients. Much of our understanding of digestive enzymes comes from studies in animals. New technologies and the
Oluwafunmilayo O Adeleye et al.
Heliyon, 6(11), e05419-e05419 (2020-11-24)
African yam beans (Sphenostylis stenocarpa), Bambara groundnut (Vigna subterranean) and Pigeon pea (Cajanus cajan) flours were extruded in a single screw extruder at two extrusion temperatures; 100 °C and 140 °C, and the effect of extrusion cooking temperature on the
Peter Layer et al.
Pancreas, 26(1), 1-7 (2002-12-25)
Treatment of steatorrhea by lipase supplementation therapy has become more successful in the last decade due to better understanding of the physiology and pathophysiology of the digestive process. Porcine lipase has been the therapeutic standard for several decades and will
T Nakamura et al.
Pancreas, 16(3), 329-336 (1998-04-21)
Pancreatic steatorrhea and pancreatic diabetes are the dominant symptoms of patients in the decompensated stage of chronic pancreatitis (CP). In this stage, the nutritional state is greatly disturbed and hypoglycemia and labile infection are involved. Pancreatic enzyme replacement therapy is
Muhammad Awais et al.
Foods (Basel, Switzerland), 9(5) (2020-05-28)
The changes in structure and digestion properties of mung bean starch due to hydrothermal treatment at various controlled temperatures were investigated. Results showed the increase in onset temperature (To) from 66.33 °C to 76.69 °C and decrease in enthalpies (∆Hg
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service