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Key Documents

Safety Information

P6386

Sigma-Aldrich

L-α-Phosphatidylethanolamine from egg yolk

Type III, 10 mg/mL in chloroform, ≥97%, solution

Synonym(s):

1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin

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About This Item

CAS Number:
39382-08-6
EC Number:
200-663-8
MDL number:
MFCD00146357
UNSPSC Code:
51191904
NACRES:
NA.25

biological source

egg yolk

Quality Level

200

type

Type III

Assay

≥97%

form

solution

concentration

10 mg/mL in chloroform

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCC)(OCCN)O

InChI

1S/C40H80NO8P/c1-3-5-7-9-11-13-15-17-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41)36-46-39(42)32-30-28-26-24-22-16-14-12-10-8-6-4-2/h38H,3-37,41H2,1-2H3,(H,44,45)/t38-/m1/s1

InChI key

NJGIRBISCGPRPF-KXQOOQHDSA-N

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Caution

Purity when prepared is 98-99%. Solutions exposed to room temperature can decompose 0.3-0.5% per day.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

P6365-22ML-PW:
P6386-BULK:
P6386-VAR:
P6386-100MG:4548173910116
P6386-50MG:
P6386-VAR-N:
P6386PROC:
P6365-4.5ML-PW:
P6386-5MG:4548173910130
P6386-25MG:4548173910123
P6365-90ML-PW:
P6386-25MG-KC:
P6386-100MG-KC:
P6386-BULK-N:
P6386-PH:

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Certificates of Analysis (COA)

Lot/Batch Number
0000403687
0000403686
0000403687
0000403686
0000373024

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Christin Stegemann et al.
Circulation, 129(18), 1821-1831 (2014-03-14)
The bulk of cardiovascular disease risk is not explained by traditional risk factors. Recent advances in mass spectrometry allow the identification and quantification of hundreds of lipid species. Molecular lipid profiling by mass spectrometry may improve cardiovascular risk prediction. Lipids
Faraz Quazi et al.
The Journal of biological chemistry, 288(48), 34414-34426 (2013-10-08)
ABCA1, ABCA7, and ABCA4 are members of the ABCA subfamily of ATP-binding cassette transporters that share extensive sequence and structural similarity. Mutations in ABCA1 cause Tangier disease characterized by defective cholesterol homeostasis and high density lipoprotein (HDL) deficiency. Mutations in
Haim Haviv et al.
The Journal of biological chemistry, 288(14), 10073-10081 (2013-02-23)
Membrane proteins interact with phospholipids either via an annular layer surrounding the transmembrane segments or by specific lipid-protein interactions. Although specifically bound phospholipids are observed in many crystal structures of membrane proteins, their roles are not well understood. Na,K-ATPase is
Heike Anders et al.
International journal of systematic and evolutionary microbiology, 64(Pt 4), 1264-1270 (2014-01-16)
A strictly aerobic, thermophilic, moderately acidophilic, non-spore-forming bacterium, strain P373(T), was isolated from geothermally heated soil at Waikite, New Zealand. Cells were filamentous rods, 0.2-0.4 µm in diameter and grew in chains up to 80 µm in length. On the
Manoj K Rathinaswamy et al.
eLife, 10 (2021-03-05)
Class I Phosphoinositide 3-kinases (PI3Ks) are master regulators of cellular functions, with the class IB PI3K catalytic subunit (p110γ) playing key roles in immune signalling. p110γ is a key factor in inflammatory diseases and has been identified as a therapeutic
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Protocols

LC/MS Analysis of Phospholipids in Milk on Asc

(soybean), ≥97%; L-α-Phosphatidylethanolamine from egg yolk, Type III, ≥97% (TLC), lyophilized powder; L-α-Phosphatidylcholine, from egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder; Sphingomyelin, from chicken egg yolk, ≥95%

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