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Safety Information

S4936

Sigma-Aldrich

Anti-Sodium Channel, Brain Type I (α subunit) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-BI, Anti-SP11I, Anti-Scna1

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41
conjugate:
unconjugated
application:
IHC
WB
clone:
polyclonal
species reactivity:
rat, mouse
citations:
1
technique(s):
immunohistochemistry: suitable using rat brain section
western blot: 1:200 using rat brain membranes

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat, mouse

technique(s)

immunohistochemistry: suitable using rat brain section
western blot: 1:200 using rat brain membranes

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Scn1a(20265)
rat ... Scn1a(81574)

Immunogen

synthetic peptide corresponding to amino acids 465-481 of the α subunit of rat type I voltage-gated sodium channel (VGSC, SP11I) with additional N-terminal lysine and tyrosine, conjugated to KLH. The epitope corresponds to the sequence in the intracellular loop between the I and II domains of type I VGSC α subunit. Homology with human is identical.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Poisonous substance

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

S4936-.2ML-PW:
S4936-.05ML:4548173347295
S4936-BULK:
S4936-VAR:
S4936-.2ML:4548173347301
S4936-.05ML-PW:


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M Noda et al.
Nature, 322(6082), 826-828 (1986-08-03)
The voltage-gated sodium channel is a transmembrane protein essential for the generation of action potentials in excitable cells. It has been reported that sodium channels purified from the electric organ of the electric eel, Electrophorus electricus, and from chick cardiac

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