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Safety Information

SAE0193

Sigma-Aldrich

Exosome standards, fluorescent

recombinant, expressed in human cells

Synonym(s):

Extracellular vesicles (EVs), Intraluminal vesicles (ILVs), Microvesicles, exosome-like vesicles

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About This Item

UNSPSC Code:
41116100
NACRES:
NA.24

recombinant

expressed in human cells

Quality Level

200

Assay

≥70% (fluorimetric)

form

solid

shipped in

dry ice

storage temp.

−70°C

General description

These recombinant EV express green fluorescent protein (GFP) on their membrane surface, making them fluorescent. Their fluorescence enables sensitive and differential trackability and thus allowing them to be used as a biological reference material, to be implemented in EV separation methods and measurement instruments. These recombinant EV share equivalent physicochemical and biochemical properties to sample EV. They may be used for quality control, data normalization, method development and accurate calibration of optical and nonoptical EV measurement.

Biochem/physiol Actions

Extracellular vesicles (Evs) are populations of cell-secreted membranous structures typically 30–150 nm in diameter.
In multicellular organisms, Evs are found in biological fluids and body tissues and involved in different physiological processes. They are also released to growth medium by cultured cells.

Evs carry markers of their cells of origin. Therefore there is a growing interest in clinical applications of EVs as biomarkers and therapies alike.

Components

Vial content: >= 1 x 10e9 particles

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAE0193-BULK:
SAE0193-VAR:
SAE0193-1VL:
SAE0193-1VL-PW:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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