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Safety Information

SML1016

Sigma-Aldrich

Camalexin

≥98% (HPLC)

Synonym(s):

3-(Thiazol-2-yl)-1H-indole, Camalexine

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About This Item

Empirical Formula (Hill Notation):
C11H8N2S
CAS Number:
135531-86-1
Molecular Weight:
200.26
MDL number:
MFCD18451889
UNSPSC Code:
12352200
PubChem Substance ID:
329825632
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

C12=CC=CC=C1NC=C2C3=NC=CS3

InChI

1S/C11H8N2S/c1-2-4-10-8(3-1)9(7-13-10)11-12-5-6-14-11/h1-7,13H

InChI key

IYODIJVWGPRBGQ-UHFFFAOYSA-N

Application

Camalexin has been used in quantification and tolerance assays in Arabidopsis thaliana leaves.

Biochem/physiol Actions

Camalexin is a phytoalexin isolated from cruciferous plants that exhibits antibacterial, antifungal, antiproliferative and cancer chemopreventive activities. Apparently, camalexin increases the ROS levels and is more effective in aggressive prostate cancer cells that express high ROS levels. In Arabidopsis thaliana, camalexin and salicylic acid confer resistance to Phytophthora capsici.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML1016-BULK:
SML1016-VAR:
SML1016-25MG:
SML1016-5MG:

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Certificates of Analysis (COA)

Lot/Batch Number
0000327545
0000327544
0000270846
0000174056
0000176582

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Jhon Venegas-Molina et al.
Scientific reports, 10(1), 10319-10319 (2020-06-27)
The plant hormones salicylic acid (SA) and jasmonic acid (JA) regulate defense mechanisms capable of overcoming different plant stress conditions and constitute distinct but interconnected signaling pathways. Interestingly, several other molecules are reported to trigger stress-specific defense responses to biotic
Hector R Huarte et al.
Plants (Basel, Switzerland), 9(9) (2020-09-24)
The association among environmental cues, ethylene response, ABA signaling, and reactive oxygen species (ROS) homeostasis in the process of seed dormancy release is nowadays well-established in many species. Alternating temperatures are recognized as one of the main environmental signals determining
Vania Michelotti et al.
BMC genomics, 19(1), 585-585 (2018-08-08)
Since 2007, bacterial canker caused by Pseudomonas syringae pv. actinidiae (Psa) has become a pandemic disease leading to important economic losses in every country where kiwifruit is widely cultivated. Options for controlling this disease are very limited and rely primarily
Mariola Piślewska-Bednarek et al.
Plant physiology, 176(1), 538-551 (2017-11-11)
Glutathione (GSH) and indole glucosinolates (IGs) exert key functions in the immune system of the model plant Arabidopsis (
Camalexin quantification in Arabidopsis thaliana leaves infected with Botrytis cinerea
Savatin DV, et al.
Bio-protocol, 5(2), e1379-e1379 (2015)
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