SRE0029

Cardiolipin solution from bovine heart

4.7-5.3 mg/mL in ethanol, ≥97% (TLC), Suitable for manufacturing of diagnostic kits and reagents

• Synonym(s): Cardiolipin solution from bovine heart
• EC Number: 200-578-6
• MDL number: MFCD00071040
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• biological source: bovine heart
• Quality Level: 400
• Assay: ≥97% (TLC)
• form: liquid
• concentration: 4.7-5.3 mg/mL in ethanol
• lipid type: phosphoglycerides
• shipped in: wet ice
• storage temp.: −20°C

Description

Application

• Site of action of the local anesthetic tetracaine in a phosphatidylcholine bilayer with incorporated cardiolipin.: This paper examines how tetracaine interacts with phosphatidylcholine bilayers containing cardiolipin, which has implications for understanding local anesthetic mechanisms (Shibata et al., 1995).

Biochem/physiol Actions

Cardiolipin is a mitochondrial phospholipid that is found in mammalian tissues in low concentrations. It is often a membrane component and can inhibit cell attachment of fibronectin, vitronectin, and type I collagen.

Physical form

Approximately 5 mg/ml in ethanol.

Other Notes

>80% polyunsaturated fatty acid content, primarily linoleic acid.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H319
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup - Solvent
• Flash Point(C): 9.7 °C - closed cup - Solvent