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Key Documents

Safety Information

T9924

Sigma-Aldrich

Troponin I from human heart

lyophilized powder

Synonym(s):

Tn-I

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About This Item

CAS Number:
77108-40-8
MDL number:
MFCD00213059
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human heart

Quality Level

200

form

lyophilized powder

purified by

affinity chromatography

technique(s)

inhibition assay: suitable

solubility

water: 5 vial/mL, clear, colorless

UniProt accession no.

P19429

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... TNNI3(7137)

Application

Troponin I from human heart can be used in studies whether the actin and aldolase can protect rabbit muscle lactate dehydrogenase inhibition by ascorbate or not.

Biochem/physiol Actions

The inhibiting subunit of troponin, responsible for preventing actin-myosin binding and ATPase activity.
Troponin I interacts with tropomyosin for regulating the contraction of striated muscle in a calcium-dependent manner. Additionally, Troponin I can also inhibits actomyosin ATPase and serves as a selective and potent inhibitor of angiogenesis in vivo and in vitro and of tumor metastasis in vivo.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

T9924-VAR:
T9924-BULK:
T9924-20UG:
T9924-20UG-PW:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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