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123048

Sigma-Aldrich

5-Amino-1-pentanol

≥92.0% (GC)

Synonym(s):

5-Aminopentanol

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About This Item

Linear Formula:
NH2(CH2)5OH
CAS Number:
Molecular Weight:
103.16
Beilstein:
1732302
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥92.0% (GC)

form

solid

refractive index

n20/D 1.4615 (lit.)

bp

120-122 °C/16 mmHg (lit.)

mp

33-35 °C (lit.)

density

0.949 g/mL at 25 °C (lit.)

SMILES string

NCCCCCO

InChI

1S/C5H13NO/c6-4-2-1-3-5-7/h7H,1-6H2

InChI key

LQGKDMHENBFVRC-UHFFFAOYSA-N

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General description

5-Amino-1-pentanol undergoes facile intramolecular cyclocondensation with piperidine and methyl or ethyl piperidine in the presence of methanol or ethanol over zeolite catalyst.

Application

5-Amino-1-pentanol has been used in the synthesis of S-glycosyl amino-acid building blocks. It has been used as starting reagent in the synthesis of aminofunctionalized 4-chloro-2,2′:6′,2′′-terpyridine.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

150.8 °F - closed cup

Flash Point(C)

66 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thomas Ziegler et al.
Nature protocols, 1(4), 1987-1994 (2007-05-10)
Complex glycosylation patterns on cell surfaces are involved in many fundamental biological processes like specific cell-cell interactions and signal transduction. Furthermore, the glycon part of glycopeptides and glycosylated proteins play a crucial role in numerous ligand-receptor interactions of biological significance.
4'-Functionalized 2, 2′ : 6′, 2′′-terpyridines as building blocks for supramolecular chemistry and nanoscience.
Schubert US,et al.
Tetrahedron, 42(28), 4705-4707 (2001)
Duho Cho et al.
Micromachines, 11(6) (2020-07-08)
A stretchable printed circuit board (PCB), which is an essential component of next-generation electronic devices, should be highly stretchable even at high levels of integration, as well as durable under repetitive stretching and patternable. Herein, an island-structured stretchable PCB composed
Zeolite catalysed intramolecular cyclization of 5-amino-1-pentanol to piperidine bases.
Reddy BN, et al.
Applied Catalysis A: General, 119(1), 23-32 (1994)
Ahmed A Eltoukhy et al.
ACS nano, 8(8), 7905-7913 (2014-07-11)
Despite intensive research effort, the rational design of improved nanoparticulate drug carriers remains challenging, in part due to a limited understanding of the determinants of nanoparticle entry and transport in target cells. Recent studies have shown that Niemann-Pick C1 (NPC1)

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