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126365

Sigma-Aldrich

Dimethylamine hydrochloride

99%

Synonym(s):

N,N-Dimethylamine hydrochloride, N-Methylmethanamine hydrochloride, Dimethylammonium chloride

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About This Item

Linear Formula:
(CH3)2NH · HCl
CAS Number:
Molecular Weight:
81.54
Beilstein:
3589311
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

solid

mp

170-173 °C (lit.)

solubility

H2O: very soluble
alcohol: soluble
diethyl ether: soluble

functional group

amine

SMILES string

Cl[H].CNC

InChI

1S/C2H7N.ClH/c1-3-2;/h3H,1-2H3;1H

InChI key

IQDGSYLLQPDQDV-UHFFFAOYSA-N

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Application

Dimethylamine hydrochloride has been used in the preparation of hexamethylmelamine-methyl-14C. It has also been used to prepare the standard solution of methylamine (MA), dimethylamine (DMA), trimethylamine (TMA), and trimethylamine-N-oxide (TMAO) while determing methylamines and trimethylamine-N-oxide in particulate matter.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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N-demethylation of the antineoplastic agent hexamethylmelamine by rats and man.
J F Worzalla et al.
Cancer research, 33(11), 2810-2815 (1973-11-01)
Mark E Erupe et al.
Journal of chromatography. A, 1217(13), 2070-2073 (2010-02-26)
An ion chromatography method with non-suppressed conductivity detection was developed for the simultaneous determination of methylamines (methylamine, dimethylamine, trimethylamine) and trimethylamine-N-oxide in particulate matter air samples. The analytes were well separated by means of cation-exchange chromatography using a 3 mM
Mojca Seručnik et al.
The journal of physical chemistry. B, 122(21), 5381-5388 (2018-01-26)
Complexes of polycations and DNA, also known as polyplexes, have been extensively studied in the past decade, as potential gene delivery systems. Their stability depends strongly on the characteristics of the polycations, as well as the nature of the added
Adam F Nugraha et al.
Polymers, 12(7) (2020-07-24)
Several methods to synthesize poly(phenylene) block copolymers through the nickel coupling reaction were attempted to reduce the use of expensive nickel catalysts in polymerization. The model reaction for poly(phenylene) having different types of dichlorobenzene derivative monomers illustrated the potential use
M L Guzmán et al.
Molecular pharmaceutics, 9(9), 2424-2433 (2012-07-20)
Therapeutic agents containing phosphate groups in their molecules have increasing therapeutic impact. The object of this study was to characterize the cationic polyelectrolyte Eudragit E100 (EuE100) as a carrier for drugs containing phosphate groups, using dexamethasone phosphate (DP) as a

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