242926

Dimethyl fumarate

97%

• Synonym(s): (2E)-2-Butenedioic acid dimethyl ester, (E)-But-2-enedioic acid dimethyl ester, Allomaleic acid dimethyl ester, Boletic acid dimethyl ester, Dimethyl trans-ethylenedicarboxylate, Methyl fumarate, trans-1,2-Ethylenedicarboxylic acid dimethyl ester, trans-Butenedioic acid dimethyl ester
• Linear Formula: CH₃OCOCH=CHCOOCH₃
• CAS Number: 624-49-7
• Molecular Weight: 144.13
• Beilstein: 774590
• EC Number: 210-849-0
• MDL number: MFCD00064438
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854591
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• bp: 192-193 °C (lit.)
• mp: 102-106 °C (lit.)
• functional group: ester
• SMILES string: [H]\C(=C(\[H])C(=O)OC)C(=O)OC
• InChI: 1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+
• InChI key: LDCRTTXIJACKKU-ONEGZZNKSA-N
• Gene Information: human ... KEAP1(9817)

Description

Application

Dimethyl fumarate can be used:

• In the preparation of an adduct [dimethyl-(+)-(11R,12R)-9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboxylate].
• As a ligand in the synthesis of Ni(II)-based catalytic system applicable in the Negishi alkylations of N-sulfonyl aziridines with organozinc reagents.
• As a ligand to synthesize zerovalent ruthenium metal complex namely Ru(η⁶-1,3,5-cyclooctatriene)(η²-dimethyl fumarate)₂.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H312,H315,H317,H335,H411
• Precautionary Statements: P261 - P264 - P271 - P273 - P280 - P302 + P352 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves