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448869

Sigma-Aldrich

Chitosan

low molecular weight

Synonym(s):

Deacetylated chitin, Poly(D-glucosamine)

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.23

Quality Level

form

powder

mol wt

50,000-190,000 Da (based on viscosity)

viscosity

20-300 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

solubility

dilute aqueous acid: soluble

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

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Application

Chitosan may be used as a flocculant, in protein precipitation, encapsulating agent and aqueous thickener.
Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Physical form

75-85% deacetylated

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ming-Hui Yang et al.
BioMed research international, 2014, 789591-789591 (2014-04-24)
Chitosan nanoparticle, a biocompatible material, was used as a potential drug delivery system widely. Our current investigation studies were the bioeffects of the chitosan nanoparticle uptake by liver cells. In this experiment, the characterizations of chitosan nanoparticles were measured by
Tsung-Lin Yang et al.
Journal of cellular and molecular medicine, 13(9A), 2853-2863 (2008-07-17)
Chitosan is a widely used biocompatible biomaterial in the tissue regeneration, but its utility and application in the tissue morphogenesis of salivary gland remains unclear. The study aimed to explore the effects of chitosan on the epithelial morphogenesis of submandibular
Ajay Vijayakumar et al.
AAPS PharmSciTech, 18(3), 875-883 (2016-07-03)
The objective of this study was to formulate and characterize properties of solid lipid nanoparticle (SLN) dispersion containing quercetin. SLN was prepared by ultrasonication method using tripalmitin and lecithin as lipid core and then the surface was coated with chitosan.
Wei-Hsuan Lo et al.
Molecules (Basel, Switzerland), 25(21) (2020-11-07)
(1) Background: Few antifungal drugs are currently available, and drug-resistant strains have rapidly emerged. Thus, the aim of this study is to evaluate the effectiveness of the antifungal activity from a combinational treatment of chitosan with a clinical antifungal drug
Mohammad Ali Khosravi Zanjani et al.
Iranian journal of pharmaceutical research : IJPR, 13(3), 843-852 (2014-10-03)
Microencapsulation as one of the most modern methods has considerable effects on probiotic survival. In this study Lactobacillus casei (ATCC 39392) and Bifidobacterium bifidum (ATCC 29521) were encapsulated using calcium alginate-gelatinized starch, chitosan coating and inulin via emulsion technique, and

Articles

Carcinogenic compounds in elastomers: 1,3-butadiene and isoprene used in elastomer manufacturing, classified as carcinogenic by IARC.

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.

Polymers, natural or synthetic, are vital in medical advancements, contributing to device and pharmaceutical development in therapy.

Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.

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