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Merck

O9808

Sigma-Aldrich

2-Oxindole

97%

Synonym(s):

2-Indolinone, Oxindole

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5 G
₩77,140
25 G
₩223,300

₩77,140


Estimated to ship onJanuary 31, 2025Details


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5 G
₩77,140
25 G
₩223,300

About This Item

Empirical Formula (Hill Notation):
C8H7NO
CAS Number:
Molecular Weight:
133.15
Beilstein:
114692
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

form:
crystals
Assay:
97%

₩77,140


Estimated to ship onJanuary 31, 2025Details


Request a Bulk Order

Quality Level

Assay

97%

form

crystals

bp

227 °C/73 mmHg (lit.)

mp

123-128 °C (lit.)

SMILES string

O=C1Cc2ccccc2N1

InChI

1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10)

InChI key

JYGFTBXVXVMTGB-UHFFFAOYSA-N

Gene Information

human ... PGR(5241)

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This Item
466921759937687227
2-Oxindole 97%

O9808

2-Oxindole

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

crystals

form

solid

form

solid

form

solid

mp

123-128 °C (lit.)

mp

85-88 °C (lit.)

mp

106-110 °C

mp

72-78 °C

bp

227 °C/73 mmHg (lit.)

bp

-

bp

-

bp

-

Gene Information

human ... PGR(5241)

Gene Information

-

Gene Information

-

Gene Information

-

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Customers Also Viewed

R Carpenedo et al.
Journal of neurochemistry, 70(5), 1998-2003 (1998-05-08)
Rats treated with oxindole (10-100 mg/kg i.p.), a putative tryptophan metabolite, showed decreased spontaneous locomotor activity, loss of the righting reflex, hypotension, and reversible coma. Brain oxindole levels were 0.05 +/- 0.01 nmol/g in controls and increased to 8.1 +/-
P B Bergqvist et al.
Pharmacology & toxicology, 85(3), 138-143 (1999-10-16)
It has previously been shown that the neurodepressant L-tryptophan metabolite oxindole is increased in the blood and brain of rats with fulminant hepatic failure and in the blood of cirrhotic patients affected by chronic hepatic encephalopathy. In the present investigation
Tao Zhang et al.
Chemical communications (Cambridge, England), 49(16), 1636-1638 (2013-01-24)
An enantioselective direct α-alkylation of 2-oxindoles with Michler's hydrol via an S(N)1-type pathway in the non-covalent activation mode using the bis-cinchona alkaloid and Brønsted acid as a co-catalyst was developed and good to high yields and enantioselectivities were obtained.
Oxindole in pathogenesis of hepatic encephalopathy.
F Moroni et al.
Lancet (London, England), 351(9119), 1861-1861 (1998-07-04)
Zhigang Yang et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 16(22), 6632-6637 (2010-04-22)
A highly enantioselective alpha-amination of 3-substituted oxindoles with azodicarboxylates catalyzed by a chiral Sc(OTf)(3)/N,N'-dioxide complex (Tf: triflate) has been developed and affords the corresponding 3-amino-2-oxindole derivatives in high yields (up to 98%) with excellent enantioselectivities (up to 99% ee). The

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