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T90808

Sigma-Aldrich

L-Tyrosine methyl ester

98%

Synonym(s):

(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid methyl ester, S-Tyrosine methyl ester

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About This Item

Linear Formula:
4-(HO)C6H4CH2CH(NH2)COOCH3
CAS Number:
1080-06-4
Molecular Weight:
195.22
Beilstein:
2372626
EC Number:
214-095-3
MDL number:
MFCD00002392
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24900583
NACRES:
NA.22

Assay

98%

form

powder with small lumps

optical activity

[α]20/D +26°, c = 2.4 in methanol

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

134-136 °C (lit.)

storage temp.

2-8°C

SMILES string

COC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI

1S/C10H13NO3/c1-14-10(13)9(11)6-7-2-4-8(12)5-3-7/h2-5,9,12H,6,11H2,1H3/t9-/m0/s1

InChI key

MWZPENIJLUWBSY-VIFPVBQESA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xavier Belda et al.
Hormones and behavior, 126, 104865-104865 (2020-09-30)
Traumatic events have been proposed to be associated with hypo-activity of the hypothalamic-pituitary-adrenal (HPA) axis, but data in animal models exposed to severe stressors are controversial and have important methodological concerns. Individual differences in resting or stress levels of corticosterone
Federico Berti et al.
Molecules (Basel, Switzerland), 25(7) (2020-04-12)
The synthesis of five hydroxycinnamoyl amides (HCAs) was accomplished and their identification and quantification in the green coffee bean samples of Coffeaarabica, Coffeacanephora, and Coffealiberica was performed. The HCAs p-coumaroyl-N-tyrosine 1b, caffeoyl-N-phenylalanine 2b, caffeoyl-N-tyrosine 3b, and p-coumaroyl-N-tryptophan 4b were characteristic
Toshihiko Hanai et al.
Carbohydrate research, 498, 108171-108171 (2020-10-14)
Glycosylation, a part of the Maillard reaction, occurs non-enzymatically in food and biological processes. The selectivity of N-glycosylation was analyzed based on the reactivity of monosaccharides with aromatic amines, including aromatic amino acids, and the degree of molecular interaction (MI)
Rodrigo Binkowski de Andrade et al.
Molecular and cellular biochemistry, 364(1-2), 253-261 (2012-02-09)
Tyrosine levels are abnormally elevated in tissues and physiological fluids of patients with inborn errors of tyrosine catabolism, especially in tyrosinemia type II, which is caused by deficiency of tyrosine aminotransferase and provokes eyes, skin, and central nervous system disturbances.
J Brtko et al.
Molecular and cellular endocrinology, 93(1), 81-86 (1993-05-01)
Various protease inhibitors (e.g. phenylmethanesulfonyl fluoride (PMSF), tosyl-phenylalanine chloromethyl ketone (TosPheCH2Cl)) and substrates (e.g., tosyl-arginine methyl ester (TosArgOMe), tryptophan methyl ester (TrpOMe)) inhibit the binding of adrenal and sex steroids to their cognate receptors (Hubbard and Kalimi (1985) Mol. Cell.
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