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141101P

Avanti

Brain Extract Polar

Avanti Research - A Croda Brand

Synonym(s):

Brain Polar Lipid Extract (Porcine)

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5 MG
₩165,344
25 MG
₩524,146

₩165,344


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5 MG
₩165,344
25 MG
₩524,146

About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

₩165,344


Please contact Customer Service for Availability
New, lower price on this item!

Request a Bulk Order

form

powder

packaging

pkg of 1 × 100 mg (141101P-100mg)
pkg of 5 × 100 mg (141101P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

lipid extracts

shipped in

dry ice

storage temp.

−20°C

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This Item
346007SML1604SML0981
NDB ≥98% (HPLC)

SML1604

NDB

assay

≥98% (HPLC)

assay

>95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: ≥10 mg/mL

solubility

DMSO: 100 mg/mL

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

storage condition

desiccated

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

-

General description

Brain Extract Polar comprises phosphatidylethanolamine as a major lipid component. It also contains phosphatidylserine and phosphatidylcholine. The minor components include the phosphatidic acid and phosphatidylinositol.
Brain Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.

Application

Brain Extract Polar has been used in parallel artificial membrane permeability assay (PAMPA) for coating membrane to evaluate blood brain-barrier permeability,[1][2] and for drug permeability studies.[3]

Biochem/physiol Actions

Lipid extracts from the mammalian tissues like brain, kidney and liver are used in generating model membranes for mimicking real membranes.[4] Brain lipid, especially the polar fraction play a key role in the inhibition of prion seeded amyloid formation.[5]

Packaging

5 mL Clear Glass Sealed Ampule (141101P-100mg)
5 mL Clear Glass Sealed Ampule (141101P-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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    Rapid screening of brain-penetrable antioxidants from natural products by blood-brain barrier specific permeability assay combined with DPPH recognition
    Zhu J, et al.
    Journal of Pharmaceutical and Biomedical Analysis, 151, 42-48 (2018)
    Laura Campello et al.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 54(1), 142-159 (2020-02-07)
    It is well established that oxidative stress and inflammation are common pathogenic features of retinal degenerative diseases. ITH12674 is a novel compound that induces the transcription factor Nrf2; in so doing, the molecule exhibits anti-inflammatory, and antioxidant properties, and affords
    Irene Paterniti et al.
    PloS one, 6(1), e15937-e15937 (2011-02-08)
    Primary traumatic mechanical injury to the spinal cord (SCI) causes the death of a number of neurons that to date can neither be recovered nor regenerated. During the last years our group has been involved in the design, synthesis and
    David S Wexler et al.
    Journal of biomolecular screening, 10(4), 383-390 (2005-06-21)
    Solubility and permeability are intimately linked in drug absorption processes. They have, however, been traditionally assayed separately. To support this linkage, a combined solubility/permeability assay was developed for determining absorption properties of chemical entities. First, solubility is determined at 4
    Estefanía de Munck et al.
    PloS one, 11(9), e0162723-e0162723 (2016-09-16)
    Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that has no effective treatment up to date. Drug discovery tasks have been hampered due to the lack of knowledge in its molecular etiology together with the limited animal

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