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857134P

Avanti

18:1 Hemi BMP (S,R)

sn-(3-oleoyl-2-hydroxy)-glycerol-1-phospho-sn-3′-(1′,2′-dioleoyl)-glycerol (ammonium salt), powder

Synonym(s):

110734

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5 MG
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5 MG
₩484,967

About This Item

Empirical Formula (Hill Notation):
C60H114NO11P
CAS Number:
Molecular Weight:
1056.52
UNSPSC Code:
51191904
NACRES:
NA.25

₩484,967


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Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (857134P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 857134P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP(OC[C@@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

InChI

1S/C60H111O11P.H3N/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-58(62)67-52-56(61)53-69-72(65,66)70-55-57(71-60(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)54-68-59(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2;/h25-30,56-57,61H,4-24,31-55

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This Item
857132P857136P857131P
packaging

pkg of 1 × 5 mg (857134P-5mg)

packaging

pkg of 1 × 5 mg (857132P-5mg)

packaging

pkg of 1 × 5 mg (857136P-5mg)

packaging

pkg of 1 × 10 mg (857131P-10mg), pkg of 1 × 5 mg (857131P-5mg)

form

powder

form

powder

form

powder

form

powder

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

manufacturer/tradename

Avanti Research - A Croda Brand 857134P

manufacturer/tradename

Avanti Research - A Croda Brand 857132P

manufacturer/tradename

Avanti Research - A Croda Brand 857136P

manufacturer/tradename

Avanti Research - A Croda Brand 857131P

General description

Hemi-bis(monoacylglycero)phosphate (hemi-BMP) is an anionic lipid, [1] comprising a glycerophosphoglycerol backbone in which three fatty acyl chains are esterified to the glycerol hydroxyls.[2]

Application

18:1 Hemi BMP (S,R) may be used in the preparation of selective organ targeting (SORT) lipid nanoparticles (LNPs) for the selective mRNA delivery to the spleen.[1]

Packaging

5 mL Clear Glass Sealed Ampule (857134P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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    Hemi-bis (monoacylglycero) phosphate composition and biosynthesis in Escherichia coli
    Garrett TA and Rose RL
    Faseb Journal (2010)
    Qiang Cheng et al.
    Nature nanotechnology, 15(4), 313-320 (2020-04-07)
    CRISPR-Cas gene editing and messenger RNA-based protein replacement therapy hold tremendous potential to effectively treat disease-causing mutations with diverse cellular origin. However, it is currently impossible to rationally design nanoparticles that selectively target specific tissues. Here, we report a strategy

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