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860583P

Avanti

12:0 SM (d18:1/12:0)

Avanti Research™ - A Croda Brand 860583P, powder

Synonym(s):

N-lauroyl-D-erythro-sphingosylphosphorylcholine

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About This Item

Empirical Formula (Hill Notation):
C35H71N2O6P
CAS Number:
474923-21-2
Molecular Weight:
646.92
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860583P-10mg)
pkg of 1 × 25 mg (860583P-25mg)
pkg of 1 × 5 mg (860583P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860583P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C35H71N2O6P/c1-6-8-10-12-14-16-17-18-19-21-22-24-26-28-34(38)33(32-43-44(40,41)42-31-30-37(3,4)5)36-35(39)29-27-25-23-20-15-13-11-9-7-2/h26,28,33-34,38H,6-25,27,29-32H2,1-5H3,(H-,36,39,40,41)/b28-26+/t33-,34+/m0/s1

InChI key

HZCLJRFPXMKWHR-FEBLJDHQSA-N

Application

12:0 SM (d18:1/12:0) has been used:
  • as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
  • as an internal standard for the quantification of serum cholesterol and triacylglycerol using liquid chromatography-mass spectrometry (LC-MS) preceded by single-step liquid-liquid extraction method
  • as an internal standard for tandem mass spectrometry analysis of lipid species

Packaging

5 mL Amber Glass Screw Cap Vial (860583P-10mg)
5 mL Amber Glass Screw Cap Vial (860583P-25mg)
5 mL Amber Glass Screw Cap Vial (860583P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jinfeng Huang et al.
Dose-response : a publication of International Hormesis Society, 18(2), 1559325820914209-1559325820914209 (2020-05-05)
Radiation biodosimeters are required urgently for fast and accurate evaluation of absorbed dose for irradiated individuals. Lipidomics has appeared as a credible technique for identification and quantification of lipid for researching biomarker of diseases. We performed a lipidomic profile on
Ya Xie et al.
Food chemistry, 319, 126547-126547 (2020-03-18)
In this research, a novel ultrasound-assisted extraction (USAE) method using a one-phase solvent (isopropanol, IPA) combined with liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QToF-MS) was developed for exhaustive profiling of egg yolk lipids, which are considered to be essential
Ursula Loizides-Mangold et al.
Journal of lipid research, 53(8), 1522-1534 (2012-05-26)
Glycosylphosphatidylinositol (GPI) anchor biosynthesis takes place in the endoplasmic reticulum (ER). After protein attachment, the GPI anchor is transported to the Golgi where it undergoes fatty acid remodeling. The ER exit of GPI-anchored proteins is controlled by glycan remodeling and
Kevin Huynh et al.
Cell chemical biology, 26(1), 71-84 (2018-11-13)
High-throughput targeted lipid profiling with liquid chromatography-mass spectrometry (LC-MS) has been used extensively to identify associations between plasma lipid species and disease states. Such methods, used to characterize larger clinical cohorts, often suffer from an inability to differentiate isomeric forms
Jone Garate et al.
Journal of the American Society for Mass Spectrometry, 31(3), 517-526 (2020-03-05)
Imaging mass spectrometry (IMS) is becoming an essential technique in lipidomics. Still, many questions remain open, precluding it from achieving its full potential. Among them, identification of species directly from the tissue is of paramount importance. However, it is not
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